广西医学2024，Vol.46Issue(5)：669-673,5.DOI:10.11675/j.issn.0253-4304.2024.05.10
血清降钙素原、C反应蛋白水平联合APACHEⅡ评分对热射病患者预后的预测价值
Predictive value of serum procalcitonin and C-reactive protein levels combined with APACHEⅡ score on prognosis in patients with heat apoplexy
摘要
Abstract
Objective To explore the predictive value of serum procalcitonin and C-reactive protein(CRP)levels combined with Acute Physiology and Chronic Health Evaluation Ⅱ(APACHEⅡ)score on prognosis in patients with heat apoplexy.Methods A total of 80 patients with heat apoplexy were selected as the research subjects.According to patients'prognosis at the occurrence of outcome events(discharge or death),patients were assigned to death group(34 cases)or survival group(46 cases).The levels of serum procalcitonin and CRP,and APACHEⅡ score were compared between patients of the two groups.The multivariate Logistic regression model was used to analyze the independent influencing factors for prognosis in patients with heat apoplexy.The value of levels of serum procalcitonin and CRP,and APACHEⅡscore for predicting prognosis in patients with heat apoplexy was evaluated by drawing receiver operating characteristic(ROC)curve.Results The results of multivariate Logistic regression analysis revealed that serum procalcitonin and CRP levels,and APACHEⅡ score were the independent influencing factors for prognosis in patients with heat apoplexy(P<0.05).Areas under the ROC curve of serum procalcitonin level,serum CRP level,APACHEⅡ score for alone and jointly predicting prognosis in patients with heat apoplexy were 0.789,0.719,0.826,and 0.877,respectively,the sensitivities were 76.47%,70.59%,82.35%,and 91.18%,respectively,and the specificities were 61.76%,53.51%,91.18%,and 96.70%,respectively,area under the ROC curve of the combined prediction of the three was greater(P<0.05).Conclusion Serum procalcitonin and CRP levels,and APACHEⅡ score were the influencing factors for prognosis in patients with heat apoplexy,and prognostic efficiency of the combined prediction of the three is relatively high.关键词
热射病/降钙素原/C反应蛋白/急性生理学与慢性健康状况评价Ⅱ/预后/预测价值Key words
Heat apoplexy/Procalcitonin/C-reactive protein/Acute Physiology and Chronic Health Evaluation Ⅱ/Prognosis/Predictive value分类
医药卫生引用本文复制引用
宋逸松,刘思琦,王睿芝,李璐,熊伟..血清降钙素原、C反应蛋白水平联合APACHEⅡ评分对热射病患者预后的预测价值[J].广西医学,2024,46(5):669-673,5.基金项目
四川省卫生健康委员会适宜技术推广项目(19SYJS07) （19SYJS07）
