蜂蜇伤后急性肾损伤危险因素的Meta分析OACSTPCD

Objective To systematically evaluate the risk factors for acute kidney injury(AKI)after wasp stings.Methods Literature related to the risk factors for AKI after wasp stings was enrolled by retrieving the databases of PubMed,Embase,Web of Science,The Cochrane Library,WanFang Data Knowledge Service Platform,China National Knowledge Infrastructure,VIP,and China Biology Medicine disc,etc.After literature screening,data extraction,and quality evaluation,the RevMan 5.3 software was used to perform Meta-analysis.Results A total of 16 case-control studies were enrolled,containing 3753 cases of patients with wasp stings.The results of Meta-analysis revealed that the elevation of peripheral blood white blood cell counts,peripheral blood white blood cell counts>20×109/L,anemia,growth of age,prolongation of wasp stings to hospital admission,increased number of wasp stings,number of wasp stings>30,gross hematuria,elevation of serum lactate dehydrogenase level,elevation of serum myoglobin level,serum albumin level≤35 g/L were the risk factors for AKI after wasp stings(P<0.05).Conclusion The elevation of peripheral blood white blood cell counts,peripheral blood white blood cell counts>20×109/L,anemia,growth of age,prolongation of wasp stings to hospital admission,increased number of wasp stings,number of wasp stings>30,gross hematuria,elevation of serum lactate dehydrogenase level,elevation of serum myoglobin level,serum albumin level≤35 g/L may increase the occurrence risk of AKI after wasp stings.