中医学报2024，Vol.39Issue(8)：1787-1796,10.DOI:10.16368/j.issn.1674-8999.2024.08.294
针刺辅助体外受精-胚胎移植治疗不孕症临床研究概述
Overview of Clinical Research on Acupuncture Assisted in Vitro Fertilization-Embryo Transfer in Treating Infertility
摘要
Abstract
Objective:To conduct a comprehensive review and analysis of clinical research on acupuncture assisted in vitro fertilization-embryo transfer(IVF-ET)in treating infertility for nearly 20 years,to provide reference for the application of acupuncture in the field of assisted reproduction.Methods:"Zhen Ci""Ti Wai Shou Jing-Pei Tai Yi Zhi""acupuncture""in vitro fertilization""embryo im-plantation","IVF"etc.were searched from CNKI,Wanfang and PubMed databases.The literature published from January 2002 to June 2022 was collected,the treatment methods were summarized,the acupoint selection rules and therapeutic effects were analyzed,and the potential mechanism of acupuncture was expounded.Results:A total of 49 clinical trials of acupuncture assisted IVF-ET in the treat-ment of infertility were included,utilizing 55 acupoints from fourteen meridians,extraordinary acupoints and ear acupoints.A total of 4 437 IVF patients received acupuncture and completed embryo transfer,of which 2 015 cases achieved clinical pregnancy.The total clinical pregnancy rate of the acupuncture group was 45.41%,which was significantly higher than that of the control group(36.39%).The treatment methods include hand acupuncture,electro-acupuncture,transcutaneous electrical acupoint stimulation,warm acupunc-ture and comprehensive acupuncture therapy.Conclusion:Acupuncture can regulate the function of hypothalamic-pituitary-ovarian axis,improve endometrial receptivity,regulate the expression of related proteins,cytokines and related genes,improve the anxiety and depression of patients,as well as increasing the pregnancy rate of women undergoing IVF-ET.关键词
不孕症/体外受精-胚胎移植/针刺Key words
infertility/in vitro fertilization-embryo transfer/acupuncture分类
医药卫生引用本文复制引用
徐梦浩,朱文馨,郑翠红..针刺辅助体外受精-胚胎移植治疗不孕症临床研究概述[J].中医学报,2024,39(8):1787-1796,10.基金项目
国家自然科学基金项目(81202757,81874388) （81202757,81874388）
