基础医学与临床2024，Vol.44Issue(8)：1189-1193,5.DOI:10.16352/j.issn.1001-6325.2024.08.1189
1型糖尿病诱发肌少症的研究进展
Research progress on the type 1 diabetes induced sarcopenia
摘要
Abstract
The prevalence of sarcopenia in type 1 diabetes is higher than that in type 2 diabetes and non-diabetes patients.Screening,diagnosis and intervention of sarcopenia in type 1 diabetes patients as early as possible is of great significance for improving the life quality of these patients.The occurrence of sarcopenia in type 1 diabetes mellitus may be closely related to the decline of skeletal muscle function caused by the decrease of insulin-like growth factor-1,activation of inflammatory factors,mitochondrial dysfunction,and accumulation of advanced glyca-tion end-products.At present,the mechanism of the occurrence and development of sarcopenia induced by type 1 diabetes is not completely clear,and the relevant new drug treatment lacks data support.Further in-depth research may bring a new direction for the prevention and treatment of sarcopenia in type 1 diabetes patients.关键词
1型糖尿病/肌少症/流行病学/发病机制/治疗Key words
type 1 diabetes mellitus/sarcopenia/epidemiological/pathogenesis/treatment分类
医药卫生引用本文复制引用
彭晴怡,许岭翎..1型糖尿病诱发肌少症的研究进展[J].基础医学与临床,2024,44(8):1189-1193,5.基金项目
中央高水平医院临床科研业务费(2022-PUMCH-B-015) （2022-PUMCH-B-015）
