中国当代医药2024，Vol.31Issue(18)：186-189,4.
水蛭及其提取物在糖尿病微血管病变中的应用及研究进展
Application and research progress of leech and its extracts in diabetic mi-croangiopathy
摘要
Abstract
Diabetic microangiopathy possesses typical clinical manifestations such as microvascular basement membrane thickening,microangioma formation,and microcirculation disorders,and is one of the most common diabetic complications.The disease not only adversely affects the quality of life of patients,but also aggravates the economic burden of patients,and has become a major lethal factor for diabetic patients.Diabetic microangiopathy most often attacks the kidneys,retina,and nervous system.Leech,as an insect medicine with significant efficacy in activating blood circulation and removing blood stasis,its main component hirudin has the strongest thrombin inhibitor to date,which can significantly improve microcircu-lation,prevent platelet aggregation and play the role of lipid regulation and stabilization of plaque.The efficacy in diabetic vasculopathy is remarkable and also provides reference for its comprehensive prevention and treatment.In this paper,the application and current research status of leech and its extracts in diabetic microangiopathy are reviewed to provide more hints for further research on leech and its extracts in related diseases.关键词
糖尿病微血管病变/血瘀/水蛭/中医病机/综述Key words
Diabetic microangiopathy/Blood stasis/Leech/Pathogenesis of traditional Chinese medicine/Review分类
医药卫生引用本文复制引用
郝馨卉,韩暄..水蛭及其提取物在糖尿病微血管病变中的应用及研究进展[J].中国当代医药,2024,31(18):186-189,4.基金项目
国家自然科学基金资助项目(82204696) （82204696）
南京中医药大学国家自然科学基金青年科学基金项目经费配套项目(XPT82204696). （XPT82204696）
