外周血炎症标志物对视网膜静脉阻塞性黄斑水肿的预测价值OACSTPCD

Objective To investigate the predictive value of peripheral blood inflammatory markers on the occurrence of retinal vein occlusive macular edema(RVO-ME),and to find the inflammatory biomarkers for predicting the occurrence of RVO-ME.Methods A total of 87 patients with RVO-ME visiting in the ophthal-mology department of this hospital from August 2020 to December 2023 served as the case group,and 87 pa-tients undergoing cataract surgery during the same period were selected as the control group.The patients in the case group were divided into the CRVO subgroup and BVRO subgroup according to the different occlusion positions.The peripheral blood platelet to lymphocyte ratio(PLR),monocyte to lymphocyte ratio(MLR)and neutrophils to lymphocytes ratio(NLR)were compared between the two groups,and the receiver operating characteristic(ROC)curve was used to evaluate the predictive value of peripheral blood PLR,MLR,NLR for the occurrence of RVO-ME.Results The peripheral blood PLR,MLR and NLR in the case group were higher than those in the control group,and the differences were statistically significant(P＜0.05).But there were no statistically significant differences in PLR,MLR and NLR between the BRVO subgroup and CRVO subgroup.The ROC curve analysis results showed that MLR[the area under the curve(AUC)=0.727,95％CI:0.651-0.803)]had better predictive value for RVO-ME occurrence.Conclusion The peripheral blood inflammatory markers PLR,MLR and NLR are closely correlated to the occurrence of RVO-ME.MLR had good predictive value for RVO-ME occurrence and may become as a inflammation biomarker to predict the occurrence RVO-ME.