临床肝胆病杂志2024，Vol.40Issue(7)：1397-1403,7.DOI:10.12449/JCH240718
三维可视化技术辅助肝细胞癌消融治疗有效性及安全性的Meta分析
Efficacy and safety of three-dimensional visualization technology in assisting ablation therapy for hepatocellular carcinoma:A Meta-analysis
摘要
Abstract
Objective To systematically evaluate the efficacy and safety of three-dimensional visualization technology in assisting ablation therapy for hepatocellular carcinoma.Methods This study was conducted according to PRISMA guidelines,with a PROSPERO registration number of CRD42023488398.PubMed,Embase,Web of Science,the Cochrane Library,CNKI,Wanfang Data,VIP,and CBM were searched for Chinese and English articles on three-dimensional visualization technology in assisting ablation therapy for hepatocellular carcinoma published up to March 2023.After quality assessment and data extraction of the studies included,RevMan 5.4 software was used to perform the meta-analysis.Results A total of 11 studies were included,with 972 patients in total,among whom 447 underwent ablation assisted by three-dimensional visualization technology(3D group)and 525 underwent ablation assisted by traditional two-dimensional imaging technology(2D group).The meta-analysis showed that compared with the 2D group,the 3D group had significantly higher success rate of first-time ablation treatment(odds ratio[OR]=5.43,95%confidence interval[CI]:2.64—11.18,P<0.001),technical efficiency(OR=6.15,95%CI:3.23—11.70,P<0.001),and complete ablation rate(OR=2.50,95%CI:1.08—5.78,P=0.03),as well as significantly lower incidence rate of major complications(OR=0.45,95%CI:0.24—0.87,P=0.02),local recurrence rate(OR=0.35,95%CI:0.17—0.72,P=0.004),and local tumor progression rate(OR=0.29,95%CI:0.16—0.50,P<0.001),while there was no significant difference in the incidence rate of mild complications between the two groups(P>0.05).Conclusion Three-dimensional visualization technology is safe and feasible in assisting ablation therapy for hepatocellular carcinoma and can improve ablation rate and reduce the incidence rate of serious complications,local recurrence rate,and local tumor progression rate,thereby showing an important application value in clinical practice.关键词
癌,肝细胞/消融技术/成像,三维/Meta分析Key words
Carcinoma,Hepatocellular/Ablation Techniques/Imaging,Three-Dimensional/Meta-Analysis引用本文复制引用
李开富,唐永成,唐浩,张玺,高本见,罗德,苏松,李波,杨小李..三维可视化技术辅助肝细胞癌消融治疗有效性及安全性的Meta分析[J].临床肝胆病杂志,2024,40(7):1397-1403,7.基金项目
四川省区域创新合作项目(2023YFQ0101) （2023YFQ0101）
四川省重点研发项目(22ZDYF1898) Regional Innovation Cooperation Project of Sichuan Province(2023YFQ0101) （22ZDYF1898）
Key Research and Development Project of Sichuan Province(22ZDYF1898) （22ZDYF1898）
