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金属离子代谢:慢性肝病中医药防治新思路OA北大核心CSTPCD

Metal ion metabolism:New ideas for the traditional Chinese medicine prevention and treatment of chronic liver disease

中文摘要英文摘要

慢性肝病具有较高的发病率,给社会和家庭带来沉重负担.研究发现金属离子代谢与慢性肝病密切相关,部分中草药可以通过调控金属离子代谢发挥防治慢性肝病的作用.目前用于治疗慢性肝病的合成药物疗效并不理想,因此多种中草药被用于慢性肝病的补充和替代疗法.本文介绍了金属离子代谢在慢性肝病中的作用和中草药及其活性成分对慢性肝病的调控作用,分析表明金属离子代谢有望为慢性肝病的研究提供新思路,为临床慢性肝病的治疗提供理论依据.对于金属离子代谢防治慢性肝病,未来还需要更多前瞻性临床研究数据,为慢性肝病患者提供有效、安全的治疗方案.

Chronic liver disease(CLD)tends to have a high incidence rate and impose a serious burden on society and families.Studies have shown that metal ion metabolism is closely associated with CLD,and some Chinese herbal medicines can play a role in the prevention and treatment of CLD by regulating metal ion metabolism.At present,the synthetic drugs currently used for the treatment of CLD fail to achieve a satisfactory effect,and therefore,a variety of Chinese herbal medicines are being used as supplementary and alternative therapies for CLD.This article introduces the role of metal ion metabolism in CLD and the regulatory effect of Chinese herbal medicines and their active components on CLD,and the analysis shows that metal ion metabolism is expected to provide new ideas for the research on CLD and a theoretical basis for the clinical treatment of CLD.For the role of metal ion metabolism in the treatment of CLD,more prospective clinical study data are needed in the future to provide effective and safe treatment regimens for patients with CLD.

郭新华;王佳慧;段雪琳;彭岳;赵铁建;郑洋;赵斌

广西中医药大学 瑞康临床医学院,南宁 530222广西中医药大学赛恩斯新医药学院,南宁 530222广西中医药大学 壮医药学院,南宁 530222广西中医药大学 基础医学院,南宁 530222

肝疾病金属离子中草药

Liver DiseasesMetal IonsDrugs,Chinese Herbal

《临床肝胆病杂志》 2024 (007)

1498-1504 / 7

国家自然科学基金(82204755,81960751);广西自然青年基金(2023GXNSFBA026274,2024GXNSFAA010235);广西中医药大学青年基金(2022QN008);广西中医药大学赛恩斯新医药学院科研项目(2023MS008,2022CX004) National Natural Science Foundation of China(82204755,81960751);Guangxi Natural Youth Foundation(2023GXNSFBA026274,2024GXNSFAA010235);Guangxi University of Traditional Chinese Medicine Youth Foundation(2022QN008);Research Project of Sains New Medical College,Guangxi University of Traditional Chinese Medicine(2023MS008,2022CX004)

10.12449/JCH240732

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