Hp、RASAL2、CDH1及TP53对胃癌前病变与早期胃癌的鉴别诊断价值OACSTPCD
Value of Hp,RASAL2,CDH1 and TP53 in Differential Diagnosis of Gastric Precancerous Lesions and Early Gastric Cancer
目的 探讨幽门螺杆菌(Hp)、RAS蛋白激活样因子2(RASAL2)、钙黏蛋白1(CDH1)及肿瘤抑制基因P53(TP53)对胃癌前病变与早期胃癌的鉴别诊断价值.方法 选取2021年6月至2023年6月收治的早期胃癌52例,根据1∶1选例原则另选取同期胃癌前病变52例、胃炎52例,分别纳入胃癌组、癌前组、胃炎组.比较3组及不同病理特征的早期胃癌患者Hp、RASAL2、CDH1、TP53阳性表达率,比较胃癌组Hp阳性、阴性患者RASAL2、CDH1…查看全部>>
Objective To investigate the value of Helicobacter pylori(Hp),RAS protein activator-like factor 2(RAS-AL2),cadherin 1(CDH1)and tumor suppressor gene P53(TP53)in differential diagnosis of gastric precancerous lesions and early gastric cancer.Methods Fifty-two patients with early gastric cancer admitted from June 2021 to June 2023 were selected,and another 52 patients with gastric precancerous lesions and 52 patients with gastritis were selected at a ratio of …查看全部>>
马越;陈伟;刘宝英;付丹丹;周彤
065000 河北廊坊,河北中石油中心医院消化内科065000 河北廊坊,河北中石油中心医院外科065000 河北廊坊,河北中石油中心医院耳鼻喉科065000 河北廊坊,河北中石油中心医院消化内科065000 河北廊坊,河北中石油中心医院消化内科
临床医学
胃肿瘤癌前病变胃炎幽门螺杆菌RAS蛋白激活样因子2钙黏蛋白1肿瘤抑制基因P53诊断价值
Gastric neoplasmsPrecancerous lesionsGastritisHelicobacter pyloriRAS protein activating-like fac-tor 2Cadherin 1Tumor suppressor gene P53Diagnostic value
《临床误诊误治》 2024 (11)
39-45,7
廊坊市科技支撑计划项目(2022013023)
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