中国临床保健杂志2024，Vol.27Issue(3)：293-296,4.DOI:10.3969/J.issn.1672-6790.2024.03.002
药物涂层球囊扩张治疗慢性肢体威胁性缺血患者胭动脉病变的效果
Clinical outcomes after drug-coated balloon angioplasty of isolated popliteal lesions in patients with chronic limb-threatening ischemia
王盛兴 1任华亮 1孙明胜 1李春民 1张望德1
作者信息
- 1. 首都医科大学附属北京朝阳医院血管外科,北京 100020
- 折叠
摘要
Abstract
Objective To explore the effectiveness and safety of drug-coated balloon(DCB)angioplasty for i-solated popliteal lesions in patients with chronic limb-threatening ischemia(CLTI).Methods A retrospective analysis was conducted among 110 CLTI patients treated at Department of Vascular Surgery,Affiliated Beijing Chaoyang Hospital of Capital Medical University from June 2019 to June 2021.The target lesions for DCB intervention were popliteal artery.The primary effectiveness outcomes were clinical improvement of Rutherford classification and wound,ischemia,foot in-fection(WIfI)classification,and clinically driven target lesion revascularization(TLR).The primary safety endpoints included all-cause mortality and amputation.Potential factors influencing amputation-free survival were analyzed by mult-ivariate analyses.Results The average age of the patients was(72.7±9.2)years.The mean lesion length was(127.6±56.8)mm.Chronic total occlusion and severe calcification occurred in 79.1％and 62.7％of patients,re-spectively.Patients with advanced limb threat accounted for 20.9％.The incidences of all-cause mortality,amputation-free survival,and clinically driven TLR during the 12-month follow-up were 11.8％,81.8％,and 12.7％,respectively.Rutherford grade and WIfI(all P＜0.001)stage were significantly improved after 3-month and 12-month follow-up.43.5％patients with advanced limb threat died or underwent major amputation during the 12-month follow-up.The Cox proportional hazards model revealed WIfI classification as independent predictors of amputation-free survival.Conclu-sions DCB angioplasty is safe and effective in isolated popliteal lesions patients with CLTI over the medium term.WIfI staging can be utilized for prognostic assessment in CLTI patients.关键词
慢性肢体威胁性缺血/血管成形术/胭动脉/危险因素Key words
Chronic limb-threatening ischemia/Angioplasty/Popliteal artery/Risk factors引用本文复制引用
王盛兴,任华亮,孙明胜,李春民,张望德..药物涂层球囊扩张治疗慢性肢体威胁性缺血患者胭动脉病变的效果[J].中国临床保健杂志,2024,27(3):293-296,4.
