乳腺癌发病与中医体质及辨证分型的相关性研究OACSTPCD

Objective To analyze the correlation between the incidence of breast cancer and traditional Chi-nese medicine(TCM)constitution and syndrome differentiation.Methods A total of 108 breast cancer patients who visited the First Affiliated Hospital of Anhui Medical University from January 2021 to June 2023 were selected as the ob-servation group,and 80 healthy women who underwent physical examination in Anhui Medical University during the same period were selected as the control group.The general information,TCM constitution and syndrome differentiation of all subjects were recorded.Multivariate logistic regression analysis was performed to identify the risk factors for breast canc-er incidence.The correlation between TCM constitution and syndrome differentiation was discussed by Spearman meth-od.Results Among the 108 patients with breast cancer,the proportions of qi-deficiency constitution(18.52％),qi-stagnation constitution(16.67％)and blood-stasis constitution(13.89％)were higher.There were statistically signifi-cant differences in the distribution of mild constitution,qi-deficiency constitution,blood-stasis constitution and qi-stagna-tion constitution between the two groups(P＜0.05),but there was no statistically significant difference in the distribu-tion of other constitutions(P＞0.05).Multivariate logistic regression analysis found that mild constitution was the pro-tective factor for breast cancer.Qi-deficiency constitution and qi-stagnation constitution were the risk factors for breast cancer(P＜0.05).Among the 108 patients with breast cancer,the most common syndrome type of breast cancer was deficiency of qi and blood(56.48％),followed by Liver depression and phlegm coagulation syndrome(18.52％),dis-harmony of thoroughfare and conception vessels(16.67％),and yin deficiency(8.33％).Qi-deficiency constitution was positively correlated with deficiency of qi and blood syndrome(P＜0.05).Yin-deficiency constitution was positively correlated with liver and kidney yin deficiency syndrome(P＜0.05).Blood-stasis constitution was positively correlated with disharmony of thoroughfare and conception vessels syndrome(P＜0.05).Qi-stagnation constitution was positively correlated with Liver depression and phlegm coagulation syndrome(P＜0.05).Conclusions Qi-deficiency constitution and qi-stagnation constitution are predisposing constitutions of breast cancer.TCM constitutions are correlated with syn-drome types of breast cancer,which affect the occurrence and development of syndrome types to a certain extent.