高膳食总抗氧化力与糖尿病的相关性研究OACSTPCD
Study on the correlation between dietary total antioxidant capacity and diabetes
目的 探讨膳食总抗氧化力(DTAC)与糖尿病发生的相关性.方法 选取2021年至2023来安县人民医院内分泌科住院的124例糖尿病患者及同期参与体检的128例成人作为研究对象,采用半定量频数调查法收集研究对象摄入的所有食物种类及数量,参照公开数据库通过血浆铁还原能力(FRAP)、自由基捕获抗氧化参数(TRAP)和Trolox等效抗氧化能力(TEAC)3个指标评估膳食总抗氧化力.按四分位法将上述3个指标数值由低到高分为4组(Q1~Q4).采用logistic回归模型分析DTAC与糖尿病相关性.结果 与健康人群对照组相比,糖尿病患者的能量、脂肪的摄入量较高,维生素C、叶酸的摄入量低.logistic回归分析结果显示,膳食TEAC 高水平组 Q3[OR 值(95%CI):0.10(0.02~0.46)]、Q4[OR值(95%CI):0.14(0.02~0.80)]发生糖尿病风险较低水平组低(P<0.05).调整模型后,膳食TEAC高水平组和TRAP高水平组发生糖尿病风险较低水平组低.结论 DTAC含量与糖尿病的发生呈负相关.
Objective To investigate the association between dietary total antioxidant capacity(DTAC)and diabetes mellitus.Methods A case-control study was conducted to select 124 diabetes patients hospitalized in the En-docrinology Department of Lai'an County People's Hospital from 2021 to 2023 and 128 adults participating in physical examination at the same time as the research objects,A semi-quantitative frequency survey was used to collect the types and quantities of all foods consumed by the subjects,and the total dietary antioxidant capacity was assessed by plasma i-ron-reducing capacity(FRAP),free radical trapping antioxidant parameter(TRAP)and Trolox equivalent antioxidant capacity(TEAC)with reference to a publicly available database.According to the quartile method,the values of the a-bove two indicators were divided into four groups(Q1-Q4)from low to high.Logistic regression model was used to ana-lyze the correlation between DTAC and diabetes and prediabetes.Results Compared to the healthy control group,the intake of energy and fat in the diabetic group was higher,and the intake of vitamin C and folate was lower(P<0.05).Logistic regression analysis showed that the risk of diabetes in the group with high dietary TEAC was lower by Q3[OR(95%CI):0.10(0.02-0.46)]and Q4[OR(95%CI):0.14(0.02-0.80)]than that in the group with low dietary TEAC.After adjusting the model,the risk of developing diabetes was reduced in the group with high levels of dietary TE-AC(P<0.05)and the group with high levels of TRAP compared with the group with low levels.Conclusions Higher DTAC is inversely related to diabetes.
王斌;潘友文;陆秀星;邱亚洲;涂修龙
来安县人民医院内分泌科,滁州 239200
糖尿病营养生理学现象膳食抗氧化能力指数危险因素
Diabetes mellitusNutritional physiological phenomenaDietOxygen radical absorbance capacityRisk factors
《中国临床保健杂志》 2024 (003)
373-377 / 5
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