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现阶段治疗干性年龄相关性黄斑变性临床试验的总结与分析

孔云珠 龚轶 邵彦

国际眼科杂志2024,Vol.24Issue(8):1240-1245,6.
国际眼科杂志2024,Vol.24Issue(8):1240-1245,6.DOI:10.3980/j.issn.1672-5123.2024.8.11

现阶段治疗干性年龄相关性黄斑变性临床试验的总结与分析

Summary and analysis of clinical trials for the treatment of dry age-related macular degeneration

孔云珠 1龚轶 1邵彦1

作者信息

  • 1. (300384)中国天津市,天津医科大学眼科医院眼视光学院眼科研究所 国家眼耳鼻喉疾病临床医学研究中心天津市分中心 天津市视网膜功能与疾病重点实验室
  • 折叠

摘要

Abstract

Age-related macular degeneration(ARMD)is one of the leading causes of irreversible blindness in the elderly.Anti-vascular endothelial growth factor(VEGF)drugs have become the first-line treatment for neovascular ARMD,which has greatly changed the prognosis.However,dry ARMD still lacks effective treatment means,focusing on prevention.At present,several clinical treatment methods are being explored,including antioxidant therapy,complement therapy,neuroprotective therapy,gene therapy,etc.This review mainly summarizes the existing clinical trials and their progress on the treatment of dry ARMD,in order to provide future prospects for the treatment of dry ARMD.A number of clinical trials have already produced promising results for the treatment of dry ARMD,and it is believed that more and more clinical trials will be successful in the near future to provide more effective treatments for patients with dry ARMD.

关键词

干性年龄相关性黄斑变性/治疗方法/临床试验/预防/治疗前景

Key words

dry age-related macular degeneration/treatment method/clinical trial/prevention/treatment prospect

引用本文复制引用

孔云珠,龚轶,邵彦..现阶段治疗干性年龄相关性黄斑变性临床试验的总结与分析[J].国际眼科杂志,2024,24(8):1240-1245,6.

基金项目

国家自然科学基金项目(No.81900891) National Natural Science Foundation of China(No.81900891) (No.81900891)

国际眼科杂志

OACSTPCD

1672-5123

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