国际眼科杂志2024，Vol.24Issue(8)：1308-1313,6.DOI:10.3980/j.issn.1672-5123.2024.8.24
SPT辅助的TPRK术后角膜上皮厚度和光密度的变化及两者的相关性
Changes in corneal epithelial thickness and optical density and their correlation after smart pulse technology-assisted transepithelial photorefractive keratectomy
摘要
Abstract
AIM:To evaluate the changes in corneal epithelial thickness(CET)and corneal optical density(CD)after smart pulse technology(SPT)-assisted transepithelial photorefractive keratectomy(TPRK)and analyze their correlation. METHODS:The prospective study included 60 patients(120 eyes)with myopia and myopic astigmatism who underwent SPT-TPRK in the ophthalmology department at the First Affiliated Hospital of Xinxiang Medical University between February and August 2023.Changes in CET and CD were evaluated preoperatively and at 1 wk,1 and 3 mo postoperatively. RESULTS:A total of 14 cases(28 eyes)were lost to follow-up,and 3 patients(6 eyes)with postoperative haze were excluded from this study,resulting in a final inclusion of 43 patients(86 eyes).At 1 wk after SPT-TPRK,CET had statistically significantly thickened compared to preoperative levels(P＜0.05),particularly in the CET at 0-2 mm central corneal area(P＜0.05).At 1 mo after SPT-TPRK,the CET at 0-2 mm area had statistically significantly decreased(P＜0.05).At 3 mo after SPT-TPRK,the CET at 0-2 mm had essentially reached preoperative levels.Postoperative CD values increased,with a positive correlation between CET in the 0-2 mm area and CD in the whole 0-2 mm area(r=0.256,P＜0.05),and a positive correlation between CET in the 2-5 mm area and CD in the anterior 2-6 mm area(r=0.319,P＜0.05). CONCLUSION:Corneal epithelial remodeling takes 3 mo in areas within 2 mm of the central cornea;areas with thinner CET have faster postoperative corneal epithelial remodeling and greater thickening in the early postoperative period;CD increases in the early postoperative period compared to the preoperative value,and in some areas,there is a positive correlation between CET and CD value.关键词
经上皮准分子激光角膜切削术(TPRK)/智能脉冲技术(SPT)/角膜上皮厚度/角膜上皮愈合/角膜光密度/屈光不正Key words
transepithelial photorefractive keratectomy(TPRK)/smart pulse technology(SPT)/corneal epithelial thickness/corneal epithelial healing/corneal optical density/refractive error引用本文复制引用
牛世阳,杨华,李彦,代志强,李新民,周予兰,张欧阳,王保君..SPT辅助的TPRK术后角膜上皮厚度和光密度的变化及两者的相关性[J].国际眼科杂志,2024,24(8):1308-1313,6.基金项目
新乡市科技攻关计划项目(No.GG2021030) Xinxiang Science and Technology Tackling Program Projects(No.GG2021030) （No.GG2021030）
