四川医学2024，Vol.45Issue(7)：715-720,6.DOI:10.16252/j.cnki.issn1004-0501-2024.07.004
常频听力正常的急性耳鸣患者大脑额叶皮层功能研究
Study on Cerebral Frontal Cortex Function in Patients with Acute Tinnitus and Normal Hearing
摘要
Abstract
Objective To investigate the characteristics of frontal cortex functional area changes in acute tinnitus patients with normal hearing by functional near-infrared spectroscopy(fNIRS)detection technology combined with anxiety and depression scale,and to study the correlation between frontal cortex function changes and anxiety and depression.Methods fNIRS was used to detect functional connectivity of frontal cortex in tinnitus patients with normal hearing and healthy group,and the degree of anxie-ty and depression in patients with tinnitus was evaluated by Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD).The correlation between the functional connectivity(FC)values of the frontal cortex and the scores of HAMA and HAHD scales in patients with acute tinnitus and normal hearing was analyzed.Results The analysis of fNIRS functional connection strength showed that the frontal cortex functional connection intensity of patients with acute tinnitus and normal hearing was signifi-cantly weakened compared with the control group.The analysis of fNIRS functional connection strength showed that the smaller the FC value of the frontal cortex of the brain in patients with acute tinnitus and normal hearing,the higher the HAMA and HAHD scores.Conclusion The function of the frontal cortex of the brain is reduced in patients with acute tinnitus and normal hearing,and there is a significant negative correlation between the functional connection strength of the frontal cortex and the score of HA-MA and HAHD in the tinnitus group.关键词
急性耳鸣/额叶/焦虑/抑郁/功能性近红外光谱Key words
acute tinnitus/prefrontal lobe/anxiety/depression/functional near-infrared spectroscopy分类
医药卫生引用本文复制引用
王媛玲,米雪芹,潘庆春,李蓓,唐晓茗,张静..常频听力正常的急性耳鸣患者大脑额叶皮层功能研究[J].四川医学,2024,45(7):715-720,6.基金项目
四川省基层卫生事业发展研究中心科研项目(编号:SWFZ22-Q-61) （编号:SWFZ22-Q-61）
