肿瘤预防与治疗2024，Vol.37Issue(7)：605-611,7.DOI:10.3969/j.issn.1674-0904.2024.07.009
液体活检在结直肠癌微小残留病灶检测中的研究及应用进展
Research and Application Progress of Liquid Biopsy in Detecting Minimal Residual Disease of Colorectal Cancer
摘要
Abstract
Minimal residual disease is a small number of tumor cells or tiny lesions that still exist in the patient during or after treatment and cannot be detected by imaging,which is the primary cause of tumor recurrence.In recent years,as a new type of biomolecular technology,liquid biopsy can help to find new biomarkers for cancer,reveal disease development trends,and provide a new perspective and dimension for cancer management and treatment by extracting the patient's body fluid and analyzing the changes in the type and quantity of metabolites in the body during the occurrence and development of cancer.This article summarizes the research and application of liquid biopsy in colorectal cancer,as well as their impact on prognosis and treatment prospects.关键词
液体活检/微小残留病灶/循环肿瘤DNA/循环肿瘤细胞/细胞外囊泡Key words
Liquid biopsy/Minimal residual disease/ctDNA/CTC/Extracellular vesicles分类
临床医学引用本文复制引用
何宗杰,李雪莹,白辰光..液体活检在结直肠癌微小残留病灶检测中的研究及应用进展[J].肿瘤预防与治疗,2024,37(7):605-611,7.基金项目
This study was supported by grants from Science and Technology Commission of Shanghai Municipality(No.21Y11912900).上海市"科技创新行动计划"医学创新研究专项(编号:21Y11912900) （No.21Y11912900）
