麦粒灸配合头穴久留针对卒中恢复期非痴呆型认知障碍认知功能及血清标志物的影响OACSTPCD
Effects of wheat-grain sized cone moxibustion plus scalp points with sustained needle retaining on the cognitive function and serum markers in non-dementia cognitive impairment in the recovery stage of cerebral stroke
目的 观察五脏俞麦粒灸配合头穴久留针治疗脑卒中恢复期非痴呆型认知障碍的临床疗效及其对血清标志物超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)、同型半胱氨酸(homocysteine,Hcy)的影响.方法 将78例脑卒中恢复期合并蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)评分为18～26分的患者随机分成治疗组40例和对照组38例.治疗组以五脏俞麦粒灸配合头穴久留针治疗,对照组采用单纯头穴久留针治疗.观察两组治疗前后MoCA评分及血清标志物各项指标(hs-CRP、Hcy水平)的变化情况.结果 两组治疗后MoCA评分较同组治疗前均显著提高,血清hs-CRP、Hcy水平均显著降低,差异均具有统计学意义(P＜0.05).治疗组治疗后MoCA评分明显高于对照组,血清hs-CRP水平明显低于对照组,差异均具有统计学意义(P＜0.05).结论 五脏俞麦粒灸联合头穴久留针的综合疗法能改善脑卒中恢复期非痴呆型认知障碍患者的认知功能,有效降低血清Hcy、hs-CRP水平.
Objective To observe the clinical efficacy of wheat-grain sized cone moxibustion at the Shu points of the five Zang organs plus scalp points with sustained needle retaining for non-dementia cognitive impairment in the recovery stage of cerebral stroke and the effects on serum markers,including hypersensitive C-reactive protein(hs-CRP)and homocysteine(Hcy).Method Seventy-eight patients in the recovery stage of cerebral stroke scored 18-26 points on the Montreal cognitive assessment(MoCA)were randomized into a treatment group of 40 cases and a control group of 38 cases.The treatment group received wheat-grain sized cone moxibustion at the Shu points of the five Zang organs plus scalp points with sustained needle retaining,and the control group only received sustained needle retaining at scalp points.Changes in the MoCA score and serum markers(hs-CPR and Hcy levels)were observed after the treatment in both groups.Result In both groups,the MoCA sore increased significantly,and the serum hs-CRP and Hcy levels decreased significantly after the treatment(P＜0.05).After the intervention,the MoCA score was markedly higher,and the serum hs-CRP level was notably lower in the treatment group than in the control group(P＜0.05).Conclusion Wheat-grain sized cone moxibustion at the Shu points of the five Zang organs plus scalp points with sustained needle retaining can improve the cognitive function and down-regulate the serum levels of Hcy and hs-CRP in patients with non-dementia cognitive impairment in the recovery stage of cerebral stroke.
曾友华;袁健辉;逄锦熙;周文姬;包烨华
杭州市中医院,杭州 310007
中医学
针灸疗法脑卒中认知障碍麦粒灸头皮针超敏C反应蛋白同型半胱氨酸
Acupuncture-moxibustionCerebral strokeCognitive impairmentWheat-grain sized cone moxibustionScalp acupunctureHypersensitive C-reactive proteinHomocysteine
《上海针灸杂志》 2024 (007)
730-733 / 4
浙江省中医药科技计划项目(2021ZB199)
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