上海针灸杂志2024，Vol.43Issue(7)：744-749,6.DOI:10.13460/j.issn.1005-0957.2024.07.0744
耳穴刮痧配合药物治疗心脾两虚型失眠症的疗效观察
Therapeutic observation of ear point Guasha plus medication for insomnia due to deficiency of the heart and spleen
摘要
Abstract
Objective To observe the clinical efficacy of ear point Guasha plus medication in treating insomnia due to deficiency of the heart and spleen.Method Ninety patients with insomnia due to deficiency of the heart and spleen were randomly divided into an observation group and a control group,with 45 cases in each group.The control group was treated with Estazolam tablets and Chinese medicine An Shen decoction,and the observation group received additional ear point Guasha.Before and after the treatment,the traditional Chinese medicine(TCM)symptom scores(the primary symptom score,secondary symptom score,and total score),Pittsburgh sleep quality index(PSQI)score,Athens insomnia scale(AIS)score,polysomnography(PSG)-related parameters(sleep latency,sleep efficiency,awake time,and total sleep time),and serum levels of orexin A(OXA)and melatonin(MT)were observed.The clinical efficacy was compared between the two groups.Result After the treatment,the TCM symptom scores,PSQI score,AIS score,sleep latency,awake time,and serum OXA level dropped in both groups,and sleep efficiency,total sleep time,and MT level increased,all showing statistical significance(P＜0.01).After the intervention,TCM symptom scores,PSQI score,AIS score,sleep latency,awake time,and serum OXA level were lower in the observation group than in the control group,and sleep efficiency,total sleep time,and MT level were higher in the observation group;the between-group differences were statistically significant(P＜0.01).The total effective rate was 91.1% in the observation group,significantly higher than 71.1% in the control group(P＜0.05).Conclusion Ear point Guasha plus An Shen decoction and conventional medication can improve sleep quality and structure in patients with insomnia due to deficiency of the heart and spleen,and the mechanism may be related to regulating serum OXA and MT levels.关键词
失眠症/心脾两虚/耳穴疗法/刮痧/安神汤/食欲素A/褪黑素Key words
Insomnia/Deficiency of the heart and spleen/Auricular point therapy/Guasha/An Shen decoction/Orexin A/Melatonin分类
医药卫生引用本文复制引用
范阳阳,刘倩,王英哲,丁改丽,谷红霞,宿英豪..耳穴刮痧配合药物治疗心脾两虚型失眠症的疗效观察[J].上海针灸杂志,2024,43(7):744-749,6.基金项目
河北省中医药管理局科研计划项目(2022356,2022029,2022357) （2022356,2022029,2022357）
