上海针灸杂志2024，Vol.43Issue(7)：757-762,6.DOI:10.13460/j.issn.1005-0957.2024.07.0757
温针灸配合依普利酮片治疗气虚血瘀型高血压的疗效观察
Observation on the therapeutic effect of warming needle combined with eplerenone tablets in the treatment of hypertension of qi deficiency induced blood stasis pattern
摘要
Abstract
Objective To observe the clinical efficacy of warming needle combined with eplerenone tablets in the treatment of hypertension of qi deficiency induced blood stasis type and its influence on lipid metabolism and quality of life.Method A total of 96 patients with hypertension of qi deficiency induced blood stasis pattern were randomly divided into a control group and an observation group,48 cases in each group.The control group was treated with eplerenone tablets orally,and the observation group was treated with warming needle on the basis of the control group.The blood pressure indicators[systolic blood pressure(SBP),diastolic blood pressure(DBP)],lipid indicators[triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C)],traditional Chinese medicine(TCM)symptom(body fatigue,nausea and chest tightness,head heavy and dizziness and excessive phlegm and anorexia)scores,quality of life scores(emotion,physical function,cognitive function and social participation)and nitric oxide(NO)and endothelin-1(ET-1)levels were observed in both groups before and after treatment.The clinical efficacy of the two groups was compared.Result The total effective rate of the observation group was 93.8%,which was significantly higher than that of the control group(72.9% )(P＜0.05).After treatment,all the indicators of blood pressure,all the TCM symptom scores and the levels of TG,TC,LDL-C and ET-1 of the two groups were significantly lower than those of the same group before the treatment,and the levels of HDL-C,NO and the scores of the quality of life of the two groups were significantly higher,and the differences were statistically significant(P＜0.05).In the observation group,the blood pressure indexes,TCM symptom scores and the levels of TG,TC,LDL-C and ET-1 were significantly lower than those in the control group,and the levels of HDL-C and NO and the quality of life scores were significantly higher than those in the control group,with statistically significant differences(P＜0.05).Conclusion Warming needle combined with eplerenone tablets are effective in treating hypertension of qi deficiency induced blood stasis pattern,which can effectively reduce blood pressure and blood lipids,improve the TCM symptoms and quality of life,increase the NO level and reduce the ET-1 level.关键词
温针疗法/气虚血瘀/高血压/脂代谢/生活质量/针药并用Key words
Warming needle therapy/Qi deficiency induced blood stasis/Hypertension/Lipid metabolism/Quality of life/Combination of acupuncture and medication分类
医药卫生引用本文复制引用
吴巧,邹盛鸿,张祺杰,张乃月..温针灸配合依普利酮片治疗气虚血瘀型高血压的疗效观察[J].上海针灸杂志,2024,43(7):757-762,6.基金项目
重庆市教育委员会科学技术研究项目(KJQN202102702) （KJQN202102702）
