上海针灸杂志2024，Vol.43Issue(7)：763-768,6.DOI:10.13460/j.issn.1005-0957.2024.07.0763
隔蒜灸配合中药治疗气阴两虚型耐多药肺结核的疗效观察
Therapeutic observation of garlic-insulated moxibustion plus Chinese medication for multidrug-resistant pulmonary tuberculosis due to dual deficiency of Qi and Yin
摘要
Abstract
Objective To observe the clinical efficacy of garlic-insulated moxibustion plus Kang Lao decoction in treating multidrug-resistant pulmonary tuberculosis due to dual deficiency of Qi and Yin and the effects on lesion absorption rate on chest CT and pulmonary function.Method A total of 130 patients with multidrug-resistant pulmonary tuberculosis due to dual deficiency of Qi and Yin were randomized into an observation group and a control group,with 65 cases in each group.The control group was treated with Kan Lao decoction,and the observation group was treated with garlic-insulated moxibustion plus Kang Lao decoction.Before and after the treatment,the following items were observed in both groups:traditional Chinese medicine(TCM)symptom score,immune function indicators[CD4﹢ and CD4﹢/CD8﹢],pulmonary function parameters[forced vital capacity(FVC),forced expiratory volume in one second(FEV1),and FEV1/FVC],and inflammatory factor levels[tissue inhibitor of metalloproteinase-1(TIMP-1),C-reactive protein(CRP),and tumor necrosis factor-α(TNF-α)].The clinical efficacy,lesion absorption rate,and adverse reaction rate were compared between the two groups.Result In the observation group,the total effective rate was 90.8%,and the lesion absorption rate was 93.9%,significantly higher than 72.3% and 75.4% in the control group(P＜0.05).In both groups,the TCM symptom scores and the levels of CD8﹢and inflammatory factors dropped significantly,and the levels of CD4﹢,CD4﹢/CD8﹢,and pulmonary function indicators increased notably after the treatment(P＜0.05).After the intervention,the TCM symptom scores and the levels of CD8﹢ and inflammatory factors were lower,and the levels of CD4﹢,CD4﹢/CD8﹢,and pulmonary function indicators were higher in the observation group than in the control group,all showing statistical significance(P＜0.05).The adverse reaction rate was 3.1% in the observation group versus 7.7% in the control group,and the between-group difference was statistically insignificant(P＞0.05).Conclusion Garlic-insulated moxibustion plus Kang Lao decoction can improve the patient's TCM symptoms and pulmonary function in treating multidrug-resistant pulmonary tuberculosis due to dual deficiency of Qi and Yin,promoting lesion absorption,enhancing immune function,and inhibiting inflammatory factor levels.关键词
灸法/抗痨汤/隔蒜灸/耐多药肺结核/气阴两虚/肺功能Key words
Moxibustion/Kang Lao decoction/Garlic-insulated moxibustion/Multidrug-resistant pulmonary tuberculosis/Dual deficiency of Qi and Yin/Pulmonary function分类
医药卫生引用本文复制引用
国美峰,李继翰,倪磊磊,荣立萍..隔蒜灸配合中药治疗气阴两虚型耐多药肺结核的疗效观察[J].上海针灸杂志,2024,43(7):763-768,6.基金项目
中医药类科学研究课题计划项目(2023272) （2023272）
