上海针灸杂志2024，Vol.43Issue(7)：785-790,6.DOI:10.13460/j.issn.1005-0957.2024.07.0785
微波针刺配合生血润肤饮治疗寻常型银屑病的疗效观察
Observation of the therapeutic efficacy of microwave needling combined with Shengxue Runfu decoction in the treatment of psoriasis vulgaris
摘要
Abstract
Objective To observe the clinical efficacy of microwave needling combined with Shengxue Runfu decoction in the treatment of psoriasis vulgaris.Method A total of 100 cases of psoriasis vulgaris were randomly divided into a control group and an observation group,50 cases in each group.The control group was treated with Shengxue Runfu decoction orally,while the observation group was treated with microwave needling on the basis of the control group.Before and after the treatment,the TCM symptom(erythema,scales,infiltrating thickening and lesion area)scores,psoriasis area and severity index(PASI)scores,serum biomarkers[angiopoietin 2(ANGPT2),vascular endothelial growth factor receptor-3(VEGFR-3)]levels and immune function indicators(CD4﹢,CD8﹢,CD4﹢/CD8﹢)were observed in the two groups,and the clinical efficacy and incidence of adverse reactions were compared between the two groups.Result The total effective rate of the observation group was 96.0%,which was significantly higher than that of the control group,which was 76.0% (P＜0.05).The TCM symptom scores,PASI scores,CD8﹢,serum ANGPT2 and VEGFR-3 levels of both groups decreased significantly,while CD4﹢ and CD4﹢/CD8﹢ increased significantly,the difference was statistically significant(P＜0.05).In the observation group,the TCM symptom scores,PASI scores,CD8﹢ and serum ANGPT2 and VEGFR-3 levels were significantly lower than those in the control group,and CD4﹢ and CD4﹢/CD8﹢ were significantly higher than those in the control group,with statistically significant differences(P＜0.05).The incidence rate of adverse reactions during treatment was 4.0% in the control group and 6.0% in the observation group,and the difference between the two groups was not statistically significant(P＞0.05).Conclusion Microwave needling combined with Shengxue Runfu decoction is an effective treatment for psoriasis vulgaris,which can effectively improve the clinical symptoms of patients,reduce the serum ANGPT2 and VEGFR-3 levels,enhance the immune function,and the safety is reliable.关键词
针灸疗法/银屑病/微波针刺/血管生成素2/血管内皮生长因子受体3/针药并用Key words
Acupuncture/Psoriasis/Microwave needling/Angiopoietin 2/Vascular endothelial growth factor receptor 3/Combination of acupuncture and medication分类
医药卫生引用本文复制引用
阮波,李铭航,叶碧珍,薛爱国,罗树雄..微波针刺配合生血润肤饮治疗寻常型银屑病的疗效观察[J].上海针灸杂志,2024,43(7):785-790,6.基金项目
广东省中医药局科研项目(20202038) （20202038）
