世界中医药2024，Vol.19Issue(12)：1820-1825,6.DOI:10.3969/j.issn.1673-7202.2024.12.018
丹白颗粒治疗盆腔炎性疾病后遗症的成本-效果分析
Cost-efficacy Analysis of Danbai Granules in Treatment of Sequelae of Pelvic Inflammatory Disease
摘要
Abstract
Objective:TreeAge Pro software was used to build a decision tree model of Danbai Granules in the treatment of sequel-ae of pelvic inflammatory diseases,and the economy of Danbai Granules and antibiotics in the treatment of sequelae of pelvic in-flammatory diseases was analyzed,so as to provide a certain basis for clinical drug selection.Methods:The cost parameters of this study were derived from the Pharmacointelligence database and related published data,and efficacy parameters were derived from a prospective real-world cohort study,so as to evaluate the short-term cost-efficacy of two treatment regiments after a 14-day model simulation.Propensity score matching(PSM)method was used to make the two groups of baseline comparable.The robustness of the research results was verified by basic analysis and sensitivity analysis,including single factor sensitivity analysis(cyclone map)and probabilistic sensitivity analysis(cost-efficacy acceptability curve and incremental cost-efficacy scatter plot).Results:The basic analysis results showed that the incremental cost-efficacy ratio(ICER)of the two groups was 293.48 yuan.Compared with the con-ventional antibiotic regimen,Danbai Granules required an additional payment of 293.48 yuan for reducing each TCM symptom score in the treatment of sequelae of pelvic inflammatory disease.Conclusion:In the case of 2021 per capita disposable income as the willing payment threshold,treatment with Danbai Granules is more economical than conventional antibiotic treatment.A higher willing payment threshold of patients indicates that treatment with Danbai Granules can be more economical.This result is similar to the ICER result of basic analysis,and ICER has good robustness.关键词
丹白颗粒/抗生素/真实世界研究/盆腔炎性疾病后遗症/倾向性评分/成本-效果分析/TreeAge Pro软件/决策树模型Key words
Danbai Granules/Antibiotics/Real-world study/Sequelae of pelvic inflammatory disease/Propensity score/Cost-ef-ficacy analysis/TreeAge Pro software/Decision tree model分类
医药卫生引用本文复制引用
杨绚如,薛晓鸥,朱玉莹,张志航..丹白颗粒治疗盆腔炎性疾病后遗症的成本-效果分析[J].世界中医药,2024,19(12):1820-1825,6.基金项目
国家重点研发计划项目(2018YFC1704106)——名老中医经验研究与推广应用一体化平台构建 （2018YFC1704106）
