生命科学仪器2024，Vol.22Issue(3)：56-58,3.DOI:10.11967/2024220618
血清CRP、Hcy水平与老年2型糖尿病患者维生素D缺乏的相关性分析
Correlation between Older People with Type 2 Diabetes's Blood CRP、Hcy Levels And Vitamin D Insufficiency
摘要
Abstract
Objective:To explore the correlation between serum levels of C-reactive protein(CRP)and homocysteine(Hcy)and vitamin D deficiency(VDD)in elderly patients with type 2 diabetes mellitus(T2DM).Methods:From September 2018 to August 2022,439 patients with T2DM hospitalized in the Department of Endocrinology of Gansu Pro-vincial People's Hospital were selected as the research objects,and they were divided into two groups:the elderly male group(238 cases)and the elderly female group(201 cases).The prevalence rate of VDD was compared between the two groups.Through correlation analysis and binary Logistic regression analysis,the correlation between the levels of inflam-matory factors CRP and Hcy and VDD was evaluated,and the risk factors of VDD were summarized.Results:Fasting blood glucose(FBG),glycosylated hemoglobin(HbA1c)、C-reactive protein(CRP)and uric acid(UA)were compared between the two groups,P>0.05.The prevalence of VDD in the two groups was compared,P>0.05;The level of serum 25-hydroxyvitamin D[25-(OH)D]was positively correlated with the course of diabetes,and negatively correlated with the levels of CRP、Hcy and PTH.CRP and Hcy are risk factors for VDD,and the course of diabetes mellitus is a protective predictor,P<0.05.Conclusion:Serum CRP and Hcy levels are negatively correlated with 25-(OH)D.Monitoring the levels of CRP and Hcy has certain clinical significance for identifying and intervening VDD.关键词
2型糖尿病/维生素D缺乏/同型半胱氨酸/C反应蛋白Key words
Type 2 diabetes/Vitamin D deficiency/Homocysteine/C-reactive protein分类
医药卫生引用本文复制引用
张媛君,常翔..血清CRP、Hcy水平与老年2型糖尿病患者维生素D缺乏的相关性分析[J].生命科学仪器,2024,22(3):56-58,3.基金项目
课题级别:武威市自然科学基金 课题编号:WW23A03RPZ011 课题名称:铁蛋白联合糖化血红蛋白在妊娠期糖尿病中诊断共性技术研究. （）
