生命科学仪器2024，Vol.22Issue(3)：149-153,5.DOI:10.11967/2024220647
多模态神经电生理指标对意识障碍的预后评估价值
Prognostic value of multimodal neuroelectrophysiological indexes in consciousness disorders
摘要
Abstract
Objective:To evaluate the prognostic value of multi-mode neuroelectrophysiological index combined de-tection in patients with consciousness disorder.Methods:48 patients with varying degrees of consciousness disorders admitted to Guangdong North People's Hospital from January 2019 to December 2023 were collected as the research subjects.All patients underwent multimodal neurophysiological examinations and were classified into different levels based on the examination results.Establish a regression model using binary logistic regression analysis and plot the corresponding ROC curve to assess the application value of the model in patient prognosis evaluation..Re-sults:Univariate analysis revealed that the EEG grading,somatosensory evoked potential grading,brainstem audi-tory evoked potential grading,visual evoked potential grading,and event-related potential grading were compared between the two groups of patients,with P<0.05.Logistic regression analysis showed that EEG had the strongest correlation with patient prognosis(OR=46.739,P=0.007),followed by BAEP grade(OR=22.737,P=0.036)and SEP grade(OR=26.513,P=0.039).By plotting the ROC curve,it was found that the AUC value corre-sponding to the combination of three electrophysiological methods was the highest,at 0.957(P=0.000).Conclu-sion:EEG、BAEP and SEP are correlated with the prognosis of patients with consciousness disorders,which provides a great reference value for evaluating the prognosis.The accuracy of the combined detection of the three methods is higher,and it is more worthy of clinical application.关键词
意识障碍/预后/脑电图/神经电生理指标Key words
Disorders of consciousness/Electroencephalogram/Prognosis/Neuroelectrophysiological indicators分类
医药卫生引用本文复制引用
王瑾,陈道朋,冯应君,刘泽宇,周礼鑫,周素芸..多模态神经电生理指标对意识障碍的预后评估价值[J].生命科学仪器,2024,22(3):149-153,5.基金项目
广东省韶关市卫生健康科研项目(项目编号Y22092) （项目编号Y22092）
