山西大学学报(自然科学版)2024,Vol.47Issue(4):717-726,10.DOI:10.13451/j.sxu.ns.2023114
前馈环与反馈环的动力学行为研究进展
Advances in the Dynamic Behavior of Feedforward Loop and Feedback Loop
摘要
Abstract
Networks are composed of a small set of recurring interaction patterns called motifs.Two of the most common motifs in the biological networks are feedforward loop(FFL)and feedback loop(FBL),which have been extensively studied,respectively.Al-though there are many instances that FFL and FBL co-exist in biological networks,there is still a lack of clear understanding on their dynamic behaviors.In this review,we first describe the structure and function of the FFL.Then,we summarize the structure and dy-namical behavior of FFL,focusing on the current status of research on two important dynamical behaviors,i.e.,multistability and os-cillation.Finally,we give some biological examples that contain both FFL and FBL,emphasizing the importance of studying the dy-namical behavior of such coupled networks.关键词
模体/前馈环/反馈环/多稳态/振荡Key words
motif/feedforward loop/feedback loop/multistability/oscillation分类
数理科学引用本文复制引用
祁宏,马中琳,曹旭清..前馈环与反馈环的动力学行为研究进展[J].山西大学学报(自然科学版),2024,47(4):717-726,10.基金项目
国家自然科学基金(12226317) (12226317)