己酮可可碱联合缬沙坦治疗糖尿病肾病疗效及对患者肾功能、血管内皮生长因子的影响OACSTPCD
Effect of pentoxifylline combined with valsartan on diabetic nephropathy and its influence on renal function and vascular endothelial growth factor
目的:探究己酮可可碱联合缬沙坦治疗糖尿病肾病的效果及对患者肾功能、血管内皮生长因子(VEGF)的影响.方法:纳入204例糖尿病肾病患者,根据区组随机化法将其分为己酮可可碱组和缬沙坦组,每组各102例.缬沙坦组给予缬沙坦进行治疗,己酮可可碱组在其基础上给予己酮可可碱.比较两组临床疗效,对比治疗前、治疗3个月后两组血肌酐(SCr)、肌酐清除率(CCr)、尿素氮(BUN)、胰岛素样生长因子1(IGF-1)、转化生长因子β1(TGF-β1)、VEGF、糖…查看全部>>
Objective:To explore the effect of pentoxifylline combined with valsartan in the treatment of diabetic ne-phropathy and its influence on renal function and vascular endothelial growth factor(VEGF).Methods:204 patients with dia-betic nephropathy were divided into observation group and control group by the block randomization method,with 102 cases in each group.The control group was treated with valsartan,and the observation group was additionally given …查看全部>>
王臣廷;刘婷;吕翠君;安向莲;袁敏;刘建凤
沧州市人民医院内分泌代谢科,河北沧州 061000河北省沧州中西医结合医院糖尿病科,河北沧州 061000沧州市人民医院内分泌代谢科,河北沧州 061000沧州市人民医院内分泌代谢科,河北沧州 061000沧州市人民医院内分泌代谢科,河北沧州 061000沧州市人民医院内分泌代谢科,河北沧州 061000
临床医学
糖尿病肾病己酮可可碱缬沙坦肾功能血管内皮生长因子生活质量
Diabetic nephropathyPentoxifyllineValsartanRenal functionVascular endothelial growth fac-torQuality of life
《陕西医学杂志》 2024 (7)
966-969,4
河北省医学科学研究计划项目(20211479)
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