妇儿健康导刊2024,Vol.3Issue(13):25-29,5.
母-胎界面滋养细胞自噬诱发胎盘植入的研究进展
Research progress of placental implantation induced by trophoblast autophagy at the maternal-fetal interface
摘要
Abstract
Autophagy is a catalytic process that maintains the homeostasis of eukaryotic cells.It mainly degrades damaged macromolecules and cytoplasmic components to provide new building materials for cell synthesis.More and more studies have shown that autophagy plays a key role in balancing immunity and inflammation.In particular,the extravillous trophoblast cells derived from embryo conduct interactive dialogue with other cells during the process of contact with the mother embryo,affecting the occurrence,implantation of embryo,and pregnancy maintenance.In the maternal-fetal interface,the expression of autophagy is closely related to the survival,invasion,and antiviral function of trophoblast,and abnormal expression will lead to a series of pathological states.Trophoblast is the main component of the placenta,and excessive invasion is the main factor for placental implantation.This article reviews recent studies on trophoblast autophagy inducing placental implantation at the maternal-fetal interface.关键词
滋养细胞/自噬/胎盘植入/母-胎界面Key words
Trophocyte/Autophagy/Placental implantation/Maternal-fetal interface分类
医药卫生引用本文复制引用
谭海霞,王彩虹,薛莲,杨少良,任柏萱,杨晓棠..母-胎界面滋养细胞自噬诱发胎盘植入的研究进展[J].妇儿健康导刊,2024,3(13):25-29,5.基金项目
甘肃省高等学校创新基金项目(2022B-193) (2022B-193)
河西学院校长基金创新团队项目(CXTD2023007). (CXTD2023007)