李伟 1曹丽君 2吴斌 1王倩 1孟亮亮 1潘亮3
作者信息
- 1. 100027,武警北京总队医院医学影像科
- 2. 100038,首都医科大学附属北京世纪坛医院放射科||100039 北京,解放军总医院第五医学中心放射科
- 3. 100010 北京,外交部机关门诊部
- 折叠
摘要
Abstract
Objective To investigate the predictive value of preoperative magnetic resonance imaging(MRI)for the postop-erative recurrence of hepatocellular carcinoma(HCC)after radiofrequency ablation.Methods A total of 80 patients with HCC who underwent radiofrequency ablation in Beijing Municipal Corps Hospital of Chinese People's Armed Police Force and the Fifth Medical Center of PLA General Hospital from July 2013 to July 2019 were selected.All patients underwent contrast-enhanced MRI examination within one week before surgery,and were followed up for recurrence within three years.According to whether they had recurrence,the patients were divided into recurrence group and non-recurrence group.The general data and MR features of the two groups were com-pared,and COX regression was used to analyze the factors affecting postoperative recurrence of HCC.Receiver operating characteristic(ROC)curve was used to analyze the efficacy of each parameter value in predicting the recurrence of HCC after radiofrequency abla-tion.Results During a 3-year follow-up,there were 19 cases(23.75%)of recurrence and 61 cases(76.25%)of no recurrence.There was no statistically significant difference in gender,age,tumor location,or alpha fetoprotein(AFP)between the two groups.Univariate analysis showed statistical differences in tumor margin(P=0.019),intratumoral fat(P=0.013),peritumoral enhancement(P=0.049),tumor capsule(P=0.003),and the spacing between tumor and large vessel(P=0.035).COX multivariate analysis showed that tumor margin(HR=3.049,95%CI:1.131-8.218),intratumoral fat(HR=0.264,95%CI:0.095-0.740),and tumor capsule(HR=0.305,95%CI:0.107-0.866)were the independent factors for postoperative recurrence in HCC patients.The area under ROC curve for the combined diagnosis of tumor margin,tumor capsule and intratumoral fat for postoperative recurrence of HCC was 0.838,with sensitivity and specificity of 84.21%and 73.77%,respectively,which had a higher predictive value than using tumor margin,tumor capsule,or intratumoral fat alone.Conclusions MR features have certain predictive value in predicting the recurrence of HCC after radiofrequency ablation,which can pro-vide reference for clinical treatment.关键词
肝癌/磁共振成像/射频消融/复发Key words
hepatocellular carcinoma/magnetic resonance imaging/radiofrequency ablation/recurrence分类
医药卫生
