现代医药卫生2024，Vol.40Issue(14)：2371-2375,5.DOI:10.3969/j.issn.1009-5519.2024.14.008
泛免疫炎症指数与原发性膜性肾病患者合并高凝状态关系研究
Study on the relationship between Pan-immune inflammatory index and hypercoagulable state in patients with idiopathic membranous nephropathy
摘要
Abstract
Objective To investigate the relationship between Pan-immune inflammation Value(PIV)and hypercoagulable state in patients with idiopathic membranous nephropathy(IMN).Methods Clinical data of 280 patients diagnosed with IMN idiopathic membranous nephropathy who underwent renal biopsy at the Department of Nephrology,Affiliated Hospital of Xuzhou Medical University from February 2020 to February 2021 were retrospectively analyzed.Patients were categorized into the hypercoagulable group(89 cases)and the control group(191 cases)based on criteria for hypercoagulability,and baseline clinical data between the two groups were compared.Results Binary logistic regression analysis revealed that PIV level(OR=1.002,95%CI 1.000-1.004,P=0.016),total cholesterol(OR=1.398,95%CI 1.190-1.642,P<0.001),and an-tithrombin Ⅲ activity(OR=0.903,95%CI 0.871-0.936,P<0.001)were independent risk factors for hy-percoagulable state in IMN patients.Conclusion PIV is an independent risk factor for hypercoagulable state in patients with IMN.Early assessment of PIV levels in IMN patients with higher PIV levels can aid in evalua-ting their coagulation status and initiating preventive measures such as anticoagulation therapy.关键词
原发性膜性肾病/泛免疫炎症指数/高凝状态/静脉血栓/相关性Key words
Idiopathic membranous nephropathy/Pan-immune inflammatory index/Hypercoagula-ble state/Venous thrombosis/Correlation分类
医药卫生引用本文复制引用
袁铭,王伟鑫,戴春..泛免疫炎症指数与原发性膜性肾病患者合并高凝状态关系研究[J].现代医药卫生,2024,40(14):2371-2375,5.基金项目
江苏省卫生健康委员会科研项目(M2020063). （M2020063）
