Abstract
Objective To investigate the effect of Baduanjin on postoperative rehabilitation of non-small cell lung cancer(NSCLC)by meta-analysis.Methods Electronic literature search was performed on PubMed,Embase,Cochrane Library,Web of Science,CNKI,CBM,VIP and Wan Fang database.The randomized con-trolled trials(RCTS)of the effect of Baduanjin in improving postoperative rehabilitation of patients with NSCLC was searched from the database establishment until April 2023.Two investigators independently screened the literature,extracted data and evaluated the risk of bias using the Cochrane risk of bias assessment tool ROB 2.0.Meta-analysis was conducted using STATA17.0 software and RevMan 5.3 software.The main outcome measures were 6-minute walking test(6MWD),self-rating Anxiety Scale(SAS),and self-rating De-pression Scale(SDS).The secondary outcome measures were Borg score,pulmonary function test[forced expi-rative volume in the first second(FEV1),forced vital capacity(FVC)],and Functional Assessment of Cancer Therapy-Lung 4.0(FACT-L 4.0).Results A total of seven articles and 437 cases were included in the litera-ture.Compared with the control group,Meta-analysis showed that,Baduanjin group at 6MWD[WMD=21.73,95%CI(16.07,27.40),P<0.001],SAS scores[WMD=-9.23,95%CI(-10.13,-8.32),P<0.001],SDS scores[WMD=-4.67,95%CI(-7.39,-1.95),P=0.001],FEV1[WMD=-0.17,95%CI(0.06,0.28),P=0.003],FVC[WMD=-0.18,95%CI(0.06,0.30),P=0.003],the physiologic condition scores in FACT-L4.0[WMD=3.94,95%CI(2.89,4.99),P<0.001],emotional status scores[WMD=3.73,95%CI(0.57,6.90),P=0.021],functional status scores[WMD=7.23,95%CI(6.07,8.38),P<0.001],and the to-tal scores[WMD=14.96,95%CI(0.35,29.57),P=0.045]were all better than the control group,the differ-ences were statistically significant.However,it was not statistically significant in the improved Borg dyspnea scores[WMD=-0.19,95%CI(-0.39,0.01),P=0.06],FEV1/FVC[SMD=0.14,95%CI(-0.24,0.51),P=0.468],social/family status scores in the FACT-L 4.0[WMD=0.44,95%CI(-0.72,1.61),P=0.455],additional status of concern scores[WMD=1.87,95%CI(-1.33,5.06),P=0.252].Conclusion Bad-uanjin can effectively improve the activity tolerance,psychological status and lung function of patients after NSCLC surgery,which is safe and feasible,but more high-quality studies are expected to confirm the improve-ment of dyspnea symptoms and quality of life.关键词
八段锦/癌,非小细胞肺/康复/Meta分析Key words
Baduanjin/Non-small cell lung cancer/Rehabilitation/Meta-analysis分类
医药卫生
