现代医药卫生2024，Vol.40Issue(14)：2460-2464,2470,6.DOI:10.3969/j.issn.1009-5519.2024.14.027
机械敏感性离子通道蛋白Piezo1与临床疾病相关性的研究进展
Research progress on the relationship between mechanosensitive ion channel protein Piezo1 and clinical diseases
摘要
Abstract
Piezo1 protein,as a novel mechanosensitive ion channel closely related to mechanical stress stimulation signals,plays a significant role in responding to mechanical stimulation and motion effects.This protein is widely distributed in the organs and tissues of the body,and has been widely concerned by the aca-demic community since its discovery.A number of highly successful scientific studies have shown that Piezo1 has important implications for the treatment of vascular,neurological,skeletal,immune,tumor and other dis-eases.Therefore,this paper reviewed the biological characteristics of Piezo1 and its correlation with clinical diseases,which provides new ideas and prospects for the study of the pathogenesis,diagnosis,treatment and prognosis monitoring of clinically related diseases.关键词
Piezo1/功能/临床疾病/机械力/蛋白/综述Key words
Piezo1/Function/Clinical disease/Mechanical force/Protein/Review分类
医药卫生引用本文复制引用
郝晓蓓,王庆,陈俊羽,翁恒,杨敏,潘娅岚,徐桂华..机械敏感性离子通道蛋白Piezo1与临床疾病相关性的研究进展[J].现代医药卫生,2024,40(14):2460-2464,2470,6.基金项目
国家自然科学基金项目(82205237) （82205237）
江苏省中医药科技发展计划项目(YB2020004) （YB2020004）
2021年度江苏省卫生健康委医学科研项目指导性项目(Z2021065) （Z2021065）
江苏省高校哲学社会科学研究项目(2024SJYB0248). （2024SJYB0248）
