协和医学杂志2024，Vol.15Issue(4)：740-746,7.DOI:10.12290/xhyxzz.2024-0407
胰腺癌围术期热点问题与管理策略
Perioperative Hot Issues and Management Strategies for Pancreatic Cancer
摘要
Abstract
Pancreatic cancer is characterized by high malignancy,low early diagnosis rates,and poor prognosis.Approximately 15%-20%of patients at initial diagnosis have resectable pancreatic cancer,20%-30%have borderline resectable pancreatic cancer,and over 50%are present with unresectable.Surgical resec-tion remains the only potentially curative treatment option available,but the unique anatomical position of the pancreatic head necessitates complex gastrointestinal reconstruction after resection,which may lead to severe complications such as grade B/C pancreatic fistulas and bleeding.Comprehensive preoperative preparation and individualized postoperative management are crucial to reducing perioperative complications,enhancing patient quality of life,and expediting the initiation of adjuvant therapy.This article reviews perioperative integrated management strategies for patients with pancreatic cancer,drawing on literature and our center's experience,in-cluding nutritional therapy,psychological support,preoperative jaundice reduction,neoadjuvant treatment,the prevention and management of pancreatic fistulas and postoperative bleeding,with the aim of improving clinical outcomes and overall survival rates.关键词
胰腺癌/围术期/热点问题/手术切除Key words
pancreatic cancer/perioperative/key issues/surgical resection分类
医药卫生引用本文复制引用
刘伟康,陈依然,杨尹默..胰腺癌围术期热点问题与管理策略[J].协和医学杂志,2024,15(4):740-746,7.基金项目
国家自然科学基金(82171722,82271764,81871954) （82171722,82271764,81871954）
北京市自然科学基金(7212111) National Natural Science Foundation of China(82171722,82271764,81871954) （7212111）
Beijing Natural Science Foun-dation(7212111) （7212111）
