协和医学杂志2024，Vol.15Issue(4)：819-824,6.DOI:10.12290/xhyxzz.2024-0207
ERCP与EUS-FNA融合技术对胰腺癌合并梗阻性黄疸的诊治效能
The Efficacy of Combined Endoscopic Ultrasound Fine-needle Aspiration and Endoscopic Retrograde Cholangiopancreatography in Same Session for the Diagnosis and Management of Pancreatic Carcinoma with Obstructive Jaundice
摘要
Abstract
Objective To explore the application value of endoscopic ultrasound fine-needle aspiration(EUS-FNA)and endoscopic retrograde cholangiopancreatography(ERCP)in the diagnosis and treatment of patients with pancreatic cancer combined with obstructive jaundice.Methods Clinical data of patients hospi-talized in the Department of Gastroenterology of Peking Union Medical College Hospital who underwent ERCP biliary stent drainage for pancreatic cancer combined with obstructive jaundice from January 1,2023 to February 26,2024 were retrospectively collected.They were categorized into the fusion technology group and the simple ERCP group according to whether EUS-FNA was performed in the same endoscopic unit.The differ-ences in pathologic diagnosis rate,ERCP drainage success rate,postoperative complication rate and patients'single hospitalization time were compared between the two groups.Results A total of 161 patients with pancre-atic cancer combined with obstructive jaundice who underwent ERCP biliary stent drainage meeting the inclusion and exclusion criteria were enrolled,of which 80 were in the fusion technique group and 81 were in the simple ERCP group.The pathological diagnosis rate in the fusion technique group was higher than that in the simple ERCP group[92.50%(74/80)vs.46.15%(12/26),P＜0.001],and the ERCP drainage suc-cess rate[82.50%(66/80)vs.86.42%(70/81),P=0.360],the overall postoperative complication rate[5.00%(4/80)vs.2.47%(2/81),P=0.443],and single hospitalization time[4(4,7)d vs.5(3,9)d,P=0.397]were not statistically different from simple ERCP groups.Conclusion The fusion of EUS-FNA and ERCP enhances the efficiency of diagnosis and treatment for pancreatic carcinoma,warranting wide-spread adoption and further research.关键词
胰腺癌/梗阻性黄疸/超声内镜引导下细针穿刺术/内镜下逆行胰胆管造影术/技术融合Key words
pancreatic cancer/obstructive jaundice/endoscopic ultrasound fine-needle aspiration/endoscopic retrograde cholangiopancreatography/fusion techniques分类
医药卫生引用本文复制引用
赵亦周,施文,冯云路,杨爱明,李佳宁,王强,伍东升,张晟瑜,吴晰,郭涛,蒋青伟,杨莹韵..ERCP与EUS-FNA融合技术对胰腺癌合并梗阻性黄疸的诊治效能[J].协和医学杂志,2024,15(4):819-824,6.基金项目
国家重点研发计划(2022YFC3602103) （2022YFC3602103）
中央高水平医院临床科研专项(2022-PUMCH-B-024,2022-PUMCH-A-177) National Key Research and Development Program of China(2022YFC3602103) （2022-PUMCH-B-024,2022-PUMCH-A-177）
National High Level Hospital Clinical Research Funding(2022-PUMCH-B-024,2022-PUMCH-A-177) （2022-PUMCH-B-024,2022-PUMCH-A-177）
