协和医学杂志2024，Vol.15Issue(4)：960-967,8.DOI:10.12290/xhyxzz.2024-0181
青少年刷牙频率与血液指标的相关性:横断面观察性研究
The Correlation between Tooth Brushing Frequency and Blood Indicators in Adolescents:A Cross-sectional Observational Study
摘要
Abstract
Objective To analyze the effects of tooth brushing frequency on blood indicators among adolescents and to preliminarily explore the effects of tooth brushing frequency on general health.Methods Using convenience sampling method,the study included the students of class 2021 of Jining No.7 Middle School and student athletes from the Jining Sports Training Center.Univariate and multivariate linear regression analyses were used to investigate the correlation between tooth brushing frequency and blood indicators such as eosinophil percentage(EOS%),eosinophil count(EOS#),basophil percentage(BAS%),basophil count(BAS#),superoxide dismutase(SOD),insulin-like growth factor 1(IGF-1)and uric acid(UA).Results A total of 305 students were included(167 from Jining No.7 Middle School,138 from Jining Sports Training Centre),with 192(62.95%)males and 113(37.05%)females.They were divided into three groups based on daily teeth brushing frequency:≤1 time(40.33%,123/305),2 times(53.77%,164/305),and≥3 times(5.90%,18/305).Univariate linear regression analysis showed that brushing twice daily was negatively correlated with EOS%,EOS#,BAS%,and BAS#(all β＞0,all P＜0.05),and positively correlated with SOD and IGF-1(both β＜0,P=0.028,P=0.007).Brushing three or more times daily was negatively correlated with UA[β(95%CI):-0.16(-0.27～0.04),P=0.008].Multivariate linear regression analysis showed that brushing twice daily was negatively correlated with BAS%(β＜0,P=0.042)and positively correlated with SOD and IGF-1(both β＞0,P=0.036,P=0.012),while brushing three or more times daily was nega-tively correlated with UA(β＜0,P=0.026).Subgroup analysis revealed that in male adolescents,brushing twice daily was positively correlated with IGF-1(β＞0,P=0.044),and in female adolescents,brushing three or more times daily was negatively correlated with UA(β＜0,P=0.014).Conclusion The adolescent tooth brushing frequency correlates with several blood indicators affecting general health,suggesting that there may be a potential association between oral health and general health.关键词
刷牙频率/血液指标/全身健康/口腔护理Key words
brushing frequency/blood indicators/whole body health/oral care分类
医药卫生引用本文复制引用
张旭,潘慧,杜函泽,翟文昊,宋帅华,郭晓湲,温琳琳,黄蕾,陈适,李道伟..青少年刷牙频率与血液指标的相关性:横断面观察性研究[J].协和医学杂志,2024,15(4):960-967,8.基金项目
国家重点研发计划(2022YFC3600203) National Key Research and Development Program of China(2022YFC3600203) （2022YFC3600203）
