抑郁症疼痛加工的行为特点及神经机制OA北大核心CHSSCDCSSCICSTPCD

The coexistence of physical pain and psychological pain,two common types of pain associated with depression,complicates the timely diagnosis of depression,alleviation of symptoms,and improvement of patients'quality of life.In-depth research into the distinct clinical manifestations and neural mechanisms of these two types of pain is of great significance for the diagnosis of depression and treatment of patients with depression.A review of the literature reveals that,in terms of behavioral indicators,individuals with depression exhibit inconsistent sensitivity to different types of physical pain and characteristics,such as a low pain threshold,long duration,and intense suffering from psychological pain,compared to healthy subjects.With respect to neural mechanisms,the patterns of physical and psychological pain in patients with depression are similar to those of healthy subjects.In the future,researchers should concentrate on the features of these two types of comorbid pain in depression,clarify the influencing factors in pain processing in depression,compare the commonalities and differences between the processing of physical and psychological pain in depression,and elucidate the functional neuroscientific changes associated with pain in depression,thus providing a basis for more accurate diagnosis and more effective treatment.