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氧化应激对母畜卵巢功能影响的研究进展

孟亚轩 刘彦 王晶 陈国顺 冯涛

畜牧兽医学报2024,Vol.55Issue(7):2825-2835,11.
畜牧兽医学报2024,Vol.55Issue(7):2825-2835,11.DOI:10.11843/j.issn.0366-6964.2024.07.005

氧化应激对母畜卵巢功能影响的研究进展

Research Progress in the Effect of Oxidative Stress on Ovarian Function in Female Livestock

孟亚轩 1刘彦 2王晶 2陈国顺 3冯涛1

作者信息

  • 1. 北京市农林科学院畜牧兽医研究所,北京 100097||北京市农林科学院—美国俄克拉荷马州立大学动物科学联合实验室,北京 100097||甘肃农业大学动物科学技术学院,兰州 730070
  • 2. 北京市农林科学院畜牧兽医研究所,北京 100097||北京市农林科学院—美国俄克拉荷马州立大学动物科学联合实验室,北京 100097
  • 3. 甘肃农业大学动物科学技术学院,兰州 730070
  • 折叠

摘要

Abstract

The ovary is an important component of the reproductive system of female livestock,and its function is regulated by many factors,among which oxidative stress,as an important cellular biological process,has been found to have a profound effect on the ovarian function.The balance between oxidation and antioxidants in the ovary plays a significant role in maintaining ovarian function.Reactive oxygen species(ROS)in the ovary participates in the regulation of oocyte growth,meiosis,ovulation,and other physiological processes.The accumulation of ROS can lead to ovarian dysfunction and affect the formation of dominant follicles.It has influence on oocyte maturation,fertilization,and subsequent embryo implantation and development.Aiming at the effects of oxidative stress on ovarian function of female animals,this paper further explored the effects of oxidative stress on oocytes,granulosa cells,follicular membrane cells and corpus luteum of female animals,and in-depth understanding of the mechanism will help reveal the internal relationship between ovarian physiology and pathology,and provide new ideas for the prevention and treatment of reproduction related diseases.

关键词

母畜/氧化应激/卵巢/卵母细胞/颗粒细胞/黄体/线粒体

Key words

female livestock/oxidative stress/ovary/oocyte/granulosa cell/corpus luteum/mitochondria

分类

农业科技

引用本文复制引用

孟亚轩,刘彦,王晶,陈国顺,冯涛..氧化应激对母畜卵巢功能影响的研究进展[J].畜牧兽医学报,2024,55(7):2825-2835,11.

基金项目

国家自然科学基金(31972575) (31972575)

北京市农林科学院课题(CZZJ202205) (CZZJ202205)

畜牧兽医学报

OA北大核心CSTPCD

0366-6964

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