畜牧兽医学报2024，Vol.55Issue(7)：3246-3254,9.DOI:10.11843/j.issn.0366-6964.2024.07.042
氨基葡萄糖对断奶仔猪生长性能、抗氧化能力及免疫功能的影响
Effects of Glucosamine on Growth Performance,Antioxidant Capacity,and Immune Function in Weaned Piglets
摘要
Abstract
This study aimed to investigate the effects of glucosamine(GlcN)on the growth performance,antioxidant capacity and immune function of weaned piglets.Two hundred and fifty 21-day-old healthy Duroc×Landrance × Yorkshire weaned piglets of similar weight were selected and randomly divided into 5 treatment groups with 5 replicates in each group.The basal diet(NC group),the basal diet+chlortetracycline 75 g·kg-1(PC group),the basal diet+GlcN 1 g·kg-1(G1 group),the basal diet+GlcN 2 g·kg-1(G2 group)and the basal diet+GlcN 3 g·kg-1(G3 group)were fed respectively for 35 days.The results showed that:1)Compared with the NC group,the ADFI and ADG of day 15 to 35 and day 1 to 35 of the other four groups were increased significantly,and the diarrhea rate of day 1 to 35 in G1,G2 and G3 groups were decreased significantly(P＜0.05).2)Compared with the NC group,the serum MDA levels of the other four groups were significantly reduced,the serum CAT activity in the G1,G2 and G3 groups were significantly increased(P＜0.05);the serum IL-1β levels of the G2 group and the serum TNF-α levels of the G1 group were significantly reduced(P＜0.05)at day 14.The serum MDA levels were significantly decreased and the serum CAT activity were significantly increased in the other four groups,and the serum T-AOC in the G2 and G3 groups were significantly increased(P＜0.05);the serum IL-10 levels in the G1 group was significantly increased,and the serum IL-1β levels in the PC group and the G1 group were significantly reduced(P＜0.05)at day 35.3)Compared with the NC group,the serum A/G in the PC,G1 and G3 groups were significantly increased,and the serum AST levels in the other four groups were decreased significantly(P＜0.05)at day 35.In summary,GlcN can improve the growth performance,reduce diarrhea rate,enhance antioxidant capacity,and immune function in weaned piglets.The appropriate dosage of GlcN is 1 g·kg-1,and its effect is better than 75 mg·kg-1 chlortetracycline.关键词
氨基葡萄糖/断奶仔猪/生长性能/抗氧化/免疫/血清生化Key words
glucosamine/weaned piglets/growth performance/antioxidant/immunity/serum biochemistry分类
农业科技引用本文复制引用
刘彬,刘彦,郑琛,冯涛..氨基葡萄糖对断奶仔猪生长性能、抗氧化能力及免疫功能的影响[J].畜牧兽医学报,2024,55(7):3246-3254,9.基金项目
国家自然科学基金项目(31972575) （31972575）
北京市农林科学院课题(CZZJ202205) （CZZJ202205）
