临床医学工程2024，Vol.31Issue(7)：813-814,2.DOI:10.3969/j.issn.1674-4659.2024.07.0813
艾普拉唑与奥美拉唑对消化性溃疡出血患者止血效果及血清炎性因子的影响比较
Comparison on Impact on Hemostatic Effect and Ser um Inflammatory Factors of Ilaprazole and Omeprazole in Patients with Peptic Ulcer Bleeding
黎燕锋 1孙文山 1陈海飞2
作者信息
- 1. 徐闻县人民医院 消化内科,广东湛江 524100
- 2. 徐闻县人民医院 胃肠镜室,广东湛江 524100
- 折叠
摘要
Abstract
Objective To compare the impact on hemostatic effect and serum inflammatory factors of ilaprazole and omeprazole in patients with peptic ulcer bleeding.Methods 80 patients with peptic ulcer bleeding admitted to our hospital from July 2022 to July 2023 were selected and randomly divided into ilaprazole group and omeprazole group,with 40 cases in each group.The efficacy-related indicators and inflammatory factor levels were compared between the two groups.Results No statistical difference was found in the rebleeding rate within 72 hours between the two groups(P>0.05).The ulcer healing time and bleeding cessation time of the ilaprazole group were shorter than those of the omeprazole group,and the blood loss was lower than that of the omeprazole group(P<0.05).After treatment,the CRP,IL-1β and TNF-α levels of the ilaprazole group were lower than those of the omeprazole group(P<0.05).Conclusions Both ilaprazole and omeprazole can effectively inhibit the peptic ulcer bleeding,but ilaprazole can significantly shorten the bleeding time,promote the ulcer healing,and inhibit the inflammatory reactions.关键词
消化性溃疡出血/艾普拉唑/奥美拉唑/止血效果/炎性因子Key words
Peptic ulcer bleeding/Ilaprazole/Omeprazole/Hemostatic effect/Inflammatory factor分类
医药卫生引用本文复制引用
黎燕锋,孙文山,陈海飞..艾普拉唑与奥美拉唑对消化性溃疡出血患者止血效果及血清炎性因子的影响比较[J].临床医学工程,2024,31(7):813-814,2.
