临床医学工程2024，Vol.31Issue(7)：817-818,2.DOI:10.3969/j.issn.1674-4659.2024.07.0817
重组人脑利钠肽联合硝普钠对心力衰竭患者血清炎性因子及心功能的影响
Impact of Recombinant Human Brain Natriuretic Peptide Combined with Sodium Nitroprusside on Serum Inflammatory Factors and Cardiac Function in Patients with Heart Failure
兰佳堃 1余清贵 1吴华锋1
作者信息
- 1. 南平市建阳第一医院心血管内科,福建南平 354200
- 折叠
摘要
Abstract
Objective To explore the impact of recombinant human brain natriuretic peptide combined with sodium nitroprusside on serum inflammatory factors and cardiac function in patients with heart failure.Methods 84 patients with heart failure admitted to our hospital from May 2021 to May 2023 were selected and randomly divided into two groups,with 42 cases in each group.The control group was treated with sodium nitroprusside,and the observation group was treated with recombinant human brain natriuretic peptide on the basis of the conrol group.Both groups were treated for 72 hours continuously.The clinical effect and safety were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the C-reactive protein(CRP),procalcitonin(PCT),brain natriuretic peptide(BNP),left ventricular end-systolic diameter(LVESD),and left ventricular end-diastolic diameter(LVEDD)of the observation group were lower than those of the control group,and the left ventricular ejection fraction(LVEF)was higher than that of the control group(P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Recombinant human brain natriuretic peptide combined with sodium nitroprusside has significant effect in the treatment of patients with heart failure,which can control the body inflammatory response,and promote the cardiac function recovery,without serious adverse reactions.关键词
心力衰竭/硝普钠/重组人脑利钠肽Key words
Heart failure/Sodium nitroprusside/Recombinant human brain natriuretic peptide分类
医药卫生引用本文复制引用
兰佳堃,余清贵,吴华锋..重组人脑利钠肽联合硝普钠对心力衰竭患者血清炎性因子及心功能的影响[J].临床医学工程,2024,31(7):817-818,2.
