临床医学工程2024，Vol.31Issue(7)：831-832,2.DOI:10.3969/j.issn.1674-4659.2024.07.0831
胃泌素-17联合幽门螺旋杆菌IgG抗体在萎缩性胃炎及早期胃癌诊断中的应用价值
Application Value of Gastrin-17 Combined with Helicobacter Pylori IgG Antibody in the Diagnosis of Atrophic Gastritis and Early Gastric Cancer
梁桂芳 1赵占军2
作者信息
- 1. 郑州公交医院 检验科,河南郑州 450003
- 2. 郑州公交医院 消化内科,河南郑州 450003
- 折叠
摘要
Abstract
Objective To explore the application value of gastrin-17(G-17)combined with Helicobacter pylori IgG antibody(HP-IgG)in the diagnosis of atrophic gastritis(AG)and early gastric cancer(GC).Methods 50 patients with early GC(early GC group)and 50 patients with AG(AG group)admitted to our hospital from January 2020 to March 2023 were selected,and another 50 healthy subjects(control group)were selected.The serum G-17 levels and HP-IgG positive rates of the three groups were compared,and the serum G-17 levels of HP-IgG positive and HP-IgG negative patients in the early GC group were compared.The diagnostic efficacy of serum G-17 combined with HP-IgG for AG and early GC was analyzed.Results The comparison of serum G-17 level and HP-IgG positive rate among the three groups:early GC group>AG group>control group.In the early GC group,the serum G-17 level of HP-IgG positive patients was higher than that of HP-IgG negative patients(P<0.05).ROC curve results showed that the AUC of serum G-17 combined with HP-IgG in the diagnosis of AG and early GC was 0.749 and 0.803,respectively,which were higher than those of each index alone.Conclusions Serum G-17 and HP-IgG in patients with AG and early GC are abnormally high,and the combined detection of the two indicators for AG and early GC has high diagnosis value.关键词
G-17/HP-IgG/萎缩性胃炎/早期胃癌/诊断价值Key words
G-17/HP-IgG/Atrophic gastritis/Early gastric cancer/Diagnostic value分类
医药卫生引用本文复制引用
梁桂芳,赵占军..胃泌素-17联合幽门螺旋杆菌IgG抗体在萎缩性胃炎及早期胃癌诊断中的应用价值[J].临床医学工程,2024,31(7):831-832,2.
