医疗卫生装备2024，Vol.45Issue(7)：17-23,7.DOI:10.19745/j.1003-8868.2024125
全身低载高频振动参数交互作用下松质骨力学行为的模拟研究
Numerical simulation study for mechanical behavior of cancellous bone under interaction of parameters of low-magnitude high-frequency vibration
摘要
Abstract
Objective To explore the mechanical behavior of cancellous bone under the interaction of whole-body low-magnitude high-frequency vibration(LMHFV)parameters,in order to provide theoretical guidance for the clinical treatment of disuse osteoporosis.Methods A three-dimensional reconstruction model was established for the cancellous bone of the mid femur by Mimics software,which was then imported into Comsol software to form a three-dimensional fluid-solid coupling finite element model.Twelve scenarios with the vibration acceleration amplitude(a)being 0.015×g,0.02×g,0.03×g and vibration frequency(f)being 30,45,60 and 100 Hz were set up for the simulation study to analyze the distribution rules of the hydrodynamic microenvironment,the stresses and the deformation displacements of cancellous bone under the interaction of LMHFV parameters.Results The bone marrow flow velocity on the surface of trabeculae and deformation displacement of bone matrix increased with the rising of a and decreased with the growing of f.Trabeculae gained high mean values of deformation displacement in case of the vibration scenario(0.015×g/0.02×g/0.03×g,30 Hz),and had high von Mises stress when LMHFV parameters were restricted within(0.02×g to 0.03×g,30 Hz to 35 Hz).Conclusion Whole-body LMHFV significantly improves the force and hydrodynamic environment of cancellous bone,and force-mediated osteoblast bioactivity can be enhanced by rationally modulating LMHFV parameters during clinical processes so as to promote osteogenesis.[Chinese Medical Equipment Journal,2024,45(7):17-23]关键词
LMHFV/力学行为/松质骨/有限元模型/骨质疏松Key words
low-magnitude high-frequency vibration/mechanical behavior/cancellous bone/finite element model/osteo-porosis分类
医药卫生引用本文复制引用
李明志,刘海英,李胜刚,张春秋..全身低载高频振动参数交互作用下松质骨力学行为的模拟研究[J].医疗卫生装备,2024,45(7):17-23,7.基金项目
国家自然科学基金面上项目(12072235) （12072235）
