疑难病杂志2024，Vol.23Issue(7)：819-822,4.DOI:10.3969/j.issn.1671-6450.2024.07.011
糖化白蛋白水平对妊娠期糖尿病孕妇新生儿不良事件的影响及预测价值
Analysis of influencing factors of neonatal adverse events in pregnant women with gestational diabetes mellitus
摘要
Abstract
Objective To analyze the effect of glycated albumin(GA)level on neonatal adverse events in pregnant women with gestational diabetes mellitus(GDM).Methods The data of 360 pregnant women with GDM who delivered at full term in the Obstetric Department of Beijing Jishuitan Hospital from January 2021 to July 2022 were retrospectively ana-lyzed.They were divided into a group with neonatal adverse events(case group,60 cases)and a group without neonatal adverse events(control group,300 cases).The pregnancy data of the two groups were compared,and the regression equa-tion was established using binary logistic regression analysis for the possible influencing factors screened by univariate analysis.Results The level of GA at the end of pregnancy was higher than that of control group(t=2324,P=0.020),the pre-pregnancy body mass index(BMI)of the case group was higher than that of the control group(t=2344,P=0.019),the fasting blood glucose at the end of pregnancy was higher than that of the control group(4.6±0.5 vs 4.5±0.5,t=2518,P=0.012),and the rate of cesarean section was higher than that of the control group(x2=5.361,P=0.021).Binary logistic re-gression equation was established,and GA[OR(95％CI)=1338(1.070-1.672)]was an independent risk factor for neonatal adverse events(P=0.011).Conclusion GA level at the end of pregnancy of GDM pregnant women is correlated with the occurrence of neonatal adverse events,and the value of this index should be attached importance in clinical work.关键词
妊娠期糖尿病/新生儿不良事件/糖化白蛋白/血糖/影响因素Key words
Gestational diabetes mellitus/Newborn adverse events/Glycated albumin/Blood glucose/Influencing factors分类
医药卫生引用本文复制引用
尚宏瑜,郑秀丽,郑蓉,王永军..糖化白蛋白水平对妊娠期糖尿病孕妇新生儿不良事件的影响及预测价值[J].疑难病杂志,2024,23(7):819-822,4.基金项目
北京积水潭医院—华诺奥美创新转化项目 Beijing Jishuitan Hospital-Huanuoaomei Innovation Transformation Project （）
