超声引导下真空辅助旋切术与传统开放手术治疗乳腺纤维瘤患者临床疗效比较OACSTPCD
Comparison of clinical efficacy between ultrasound-guided vacuum assisted circumcision and traditional open surgery for the treatment of breast fibroma patients
目的 探讨超声引导下真空辅助旋切术治疗乳腺纤维瘤的效果及对术后恢复时间、乳晕区感觉神经功能的影响.方法 选取2020年5月-2022年5月玉林市红十字会医院甲状腺乳腺外科收治的乳腺纤维瘤患者120例,根据随机数字表法分为观察组(n=60)和对照组(n=60),2组均采用超声诊断仪检查及诊断,其中对照组采用传统开放手术治疗,观察组采用超声引导下真空辅助旋切术治疗.比较2组患者的手术相关指标、病灶切除率、血清疼痛应激指标[神经肽Y(NPY)、5-羟色胺(5-HT)、前列腺素(PGE2)]、乳晕区感觉神经功能、术后切口愈合满意度、术后并发症.结果 观察组切口长度、手术时间、术后恢复时间及出血量均短于/少于对照组,差异有统计学意义(t=38.366、10.435、7.207、20.539,P均＜0.001);观察组病灶切除成功率为96.67％(58/60),对照组病灶切除率为100％(60/60),2组比较差异无统计学意义(x2=2.034,P＞0.05);术后24 h观察组血清NPY、5-HT、PGE2水平均低于对照组(t=4.325、3.787、4.619,P＜0.001);在术后1周和1个月,观察组和对照组乳晕区感觉神经功能正常、减退和缺失患者例数比较差异无统计学意义(P＞0.05);术后1个月,观察组和对照组患者的总满意度差异无统计学意义(P＞0.05);观察组患者术侧疼痛、皮肤瘙痒、切口色素沉着和病灶残留等术后并发症总发生率低于对照组(x2=4.615,P=0.032).结论 超声引导下真空辅助旋切术治疗乳腺纤维瘤,可缩短患者术后恢复时间,降低血清疼痛应激指标,减少术后并发症.
Objective To explore the curative effect of ultrasound-guided vacuum-assisted excision on mammary fibroma and its influences on postoperative recovery time and sensory nerve function in areola region.Methods A total of 120 patients with breast fibroma admitted to the Thyroid and Breast Surgery Department of Yulin Red Cross Hospital from May 2020 to May 2022 were selected.According to random number table method,they were divided into observation group(n=60)and control group(n=60).All were examined and diagnosed with ultrasonic diagnostic apparatus.The control group was treated with traditional open surgery,while observation group was treated with ultrasound-guided vacuum-assis-ted excision.The surgical related indexes,focal excision rate,serum pain stress markers[neuropeptide Y(NPY),5-hydroxytryptamine(5-HT),prostaglandin(PGE2)],sensory nerve function in areola region,satisfaction with postoperative wound healing and postoperative complications were compared between the two groups.Results The incision length,oper-ation time and postoperative recovery time of the observation group were shorter than those of the control group,and the blood loss was less than that of the control group(t=38.366,10.435,7.207,20.539,all P＜0.001).There was no significant difference in success rate of focal resection between observation group and control group(96.67％vs.100％,x2=2.034,P＞0.05).The levels of NPY,5-HT and PGE2 in observation group were lower than those in control group 24 h after operation(t=4.325,3.787,4.619,all P＜0.001).At 1 week and 1 month after surgery,there was no significant difference in number of pa-tients with normal sensory nerve function,functional impairment and loss between the two groups(P＞0.05).One month af-ter operation,there was no significant difference in total satisfaction between the two groups(P＞0.05).The incidence of postoperative complications(pain of affected site,skin pruritus,incision pigmentation,lesion residual)in observation group was lower than that in control group(x2=4.615,P=0.032).Conclusion Ultrasound-guided vacuum-assisted excision can better shorten postoperative recovery time,reduce serum pain stress index,and reduce postoperative complications in pa-tients with mammary fibroma.
莫鹏;杨开宇;梁戈阳;黄森松;郑冰
537000 广西玉林,玉林市红十字会医院超声科537000 广西玉林,玉林市红十字会医院甲状腺乳腺外科
临床医学
乳腺纤维瘤超声引导真空辅助旋切术疗效
Mammary fibromaUltrasound-guidedVacuum-assisted excisionTherapeutic effect
《疑难病杂志》 2024 (007)
846-849,855 / 5
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