吡非尼酮及其衍生物的研究进展OA
Research Progress of Pirfenidone and Its Derivatives
综述了吡非尼酮的研发历程,并对吡非尼酮的药理活性研究进行了总结.以吡非尼酮为先导物,发展了多个系列的衍生物,这些衍生物具有较好的生物活性,为开发设计结构更独特、活性更好的新药提供理论依据.
This article reviews the research and development process of pirfenidone and summarizes the research on the pharmacological activity of pirfenidone.Using pirfenidone as the lead compound,multiple series of derivatives have been developed.These derivatives have good biological ac-tivity and provide theoretical basis for the development and design of novel drugs with more unique structures and better activity.
张讯;陈聪地;姚莎;王小月;杜琳;王洁雪;常波
成都师范学院 化学与生命科学学院,功能分子结构优化与应用四川省高校重点实验室,四川 成都 611130
药学
吡非尼酮衍生物药理纤维化
PirfenidoneDerivativesPharmacologyFibrosis
《云南化工》 2024 (007)
17-20 / 4
2021年四川省大学生创新创业训练计划项目(S202114389086).
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