芙蓉尿感清治疗尿路感染作用机制的网络药理学分析OA
Network Pharmacological Analysis of the Mechanism of Furong Niaoganqing in the Treatment of Urinary Tract Infection
目的 基于网络药理学探析芙蓉尿感清治疗尿路感染的潜在靶点、信号通路及作用机制.方法 通过TCMSP数据库及文献检索获取芙蓉尿感清的药物活性成分及作用靶点,并借助Uniprot数据库校正基因名称;通过Genecards、DisGeNET数据库收集治疗尿路感染的相关靶点,利用Venny2.1获取药物-疾病交集靶点;利用STRING数据库构建交集靶点的蛋白质-蛋白质相互作用(PPI)网络,运用软件Cytoscape对核心靶点进行拓扑分析;采用DAVID…查看全部>>
Objective To explore the potential targets,signaling pathways and mechanism of FurongNiaoganqing in the treatment of urinary tract infection based on network pharmacology.Methods The active components and targets of Furong Niaoganqing were obtained by TCMSP database and literature retrieval,and the gene name was corrected by Uniprot database.Genecards and DisGeNET databases were used to collect relevant targets for the treatment of urinary tract infection,an…查看全部>>
李文花;王岚
湖北中医药大学中医学院,湖北武汉 430065湖北中医药大学第一临床学院,湖北武汉 430065||湖北中医药大学附属医院肾病科/湖北省中医药研究院,湖北武汉 430061
临床医学
尿路感染芙蓉尿感清王柏枝网络药理学
Urinary tract infectionFurong NiaoganqingWANG Bai-zhiNetwork pharmacology
《医学信息》 2024 (14)
1-5,5
1.湖北省教育厅科研项目(编号:D20202003)2.王柏枝名老中医工作室(编号:国中医药人教涵[2022]75号)
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