医学信息2024，Vol.37Issue(14)：33-37,5.DOI:10.3969/j.issn.1006-1959.2024.14.006
陇南段铁路职工超重肥胖与血脂异常的动态队列研究
Dynamic Cohort Study on Overweight,Obesity and Dyslipidemia Among Railway Workers in Longnan Section
摘要
Abstract
Objective To understand the prevalence of dyslipidemia in railway workers in Longnan section of Lanzhou-Chongqing Railway,and to explore the correlation between the risk of dyslipidemia and overweight and obesity,so as to provide scientific basis for the prevention and treatment of dyslipidemia in railway workers.Methods From January 2016 to December 2021,596 railway workers in Longnan section of Lanzhou-Chongqing Railway with at least one follow-up in the same medical institution and no dyslipidemia at baseline were selected as the research objects.According to the"Guidelines for the Prevention and Treatment of Dyslipidemia in Chinese Adults(2016 Revision)"and the last detection of TG,TC,LDL-C and HDL-C,the subjects were divided into dyslipidemia group and normal blood lipid group,with 190 workers(31.88％)and 406 workers(68.12％),respectively.Cox proportional hazard model was used to analyze the correlation between overweight,obesity and dyslipidemia.Kaplan-Meier method was used to draw the cumulative probability curve of dyslipidemia in railway workers,and Log-rank method was used to compare between groups.Results A total of 596 railway workers were included in the study,including 531 males(89.09％)and 65 females(10.91％).The median age at baseline was 24 years old(IQR=3).During the 5-year follow-up period,a total of 190 workers(31.88％)had abnormal blood lipids,and the proportion of dyslipidemia in the obese group was higher than that in the overweight and normal groups,and the proportion of dyslipidemia in the overweight group was higher than that in the normal group(P＜0.001).During the baseline and follow-up period,the levels of BMI,TG,TC,LDL-C,HDL-C and blood glucose in the dyslipidemia group were higher than those in the normal lipid group(Pbaseline＜0.01,Pfollow-up＜0.001).After adjusting for gender,age,diastolic blood pressure,systolic blood pressure and blood glucose in the Cox proportional hazard model,the risk of dyslipidemia in the overweight and obese groups was 1.57(1.12-2.21)and 2.10(1.09-4.05),respectively.The cumulative probability curve showed that the cumulative probability of dyslipidemia in the normal group was lower than that in the overweight group(P＜0.001)and the obese group(P＜0.01).Conclusion Overweight and obesity increase the risk of dyslipidemia.Monitoring the BMI level of railway workers is of great significance for the prevention of dyslipidemia.关键词
铁路职工/血脂异常/BMI/队列研究Key words
Railway workers/Dyslipidemia/BMI/Cohort study分类
医药卫生引用本文复制引用
杨少华,王少华,徐国祥,刘健生,郭强..陇南段铁路职工超重肥胖与血脂异常的动态队列研究[J].医学信息,2024,37(14):33-37,5.基金项目
兰州铁路局集团公司2022年科技发展项目计划(编号:LZJKY2022002-2) （编号:LZJKY2022002-2）
