摘要
Abstract
Objective To analyze the diagnostic performance of shear wave elastography(SWE)and pulsed wave Doppler(PW)in benign and malignant breast lesions,and to explore the potential relationship between elastic modulus and blood flow parameters.Methods A total of 349 patients(356 lesions in total)who were admitted to the First Affiliated Hospital of Anhui Medical University from August 2019 to February 2021 were selected as the research objects.All patients underwent PW and SWE examinations.The obtained SWE parameters included E-max,E-mean,E-min,E-sd,and E-ratio,and the PW parameters included PI,RI,PSV,and EDV.The pathological results were used as the gold standard to analyze the diagnostic efficacy of blood flow parameters and elastic modulus values for breast lesions,and to explore the correlation between SWE and PW parameters.Results According to the pathological results,the lesions were divided into benign group and malignant group,the results showed that There were significant differences in E-max,E-mean,E-min,E-sd,E-ratio,PI,RI,PSV and EDV between the two groups(P＜0.05),while The AUC of E-max and E-sd were the best,which were 0.912 and 0.903,respectively.When E-max＞84.45 Kpa was used as the cut-off value,the sensitivity of E-max in the diagnosis of benign and malignant breast lesions was 91.51％.When E-sd＞22.35 Kpa was used as the cut-off value,the specificity of E-sd in the diagnosis of benign and malignant breast lesions was 86.38％.When RI＞0.70 was used as the cut-off value,the specificity of RI in the diagnosis of benign and malignant breast lesions was 89.00％.When PI＞1.07 was used as the cut-off value,the sensitivity of PI in the diagnosis of benign and malignant breast lesions was 85.45％.Correlation analysis showed that E-max was moderately correlated with Pl(r=0.793,P＜0.05)and RI(r=0.767,P＜0.05),and E-sd was moderately correlated with PI(r=0.752,P＜0.05)and RI(r=0.731,P＜0.05).In the malignant group,there was a correlation between E-max,E-sd and PI,RI,and there was no correlation between the parameters in the benign group.Conclusion The diagnostic performance of SWE and PW parameters for breast lesions is similar,and there is a correlation between SWE and PW parameters in breast lesions,especially in malignant lesions,which can reflect the internal relationship between the elastic characteristics and vascular characteristics of breast lesions.关键词
剪切波弹性成像/脉冲多普勒/乳腺病变/超声参数Key words
Shear wave elastography/Pulsed wave Doppler/Breast lesions/Ultrasound parameters分类
医药卫生
