医学信息2024，Vol.37Issue(14)：188-192,5.DOI:10.3969/j.issn.1006-1959.2024.14.040
痛风性关节炎并发高脂血症的发病机制及从脾论治的研究现状
Pathogenesis of Gouty Arthritis Complicated with Hyperlipidemia and the Research Status of Treatment from the Spleen
梁德风 1江超宇 1覃姻姻 1徐家馨 1庞学丰1
作者信息
- 1. 广西中医药大学附属瑞康医院风湿免疫科,广西 南宁 530000
- 折叠
摘要
Abstract
Gouty arthritis(GA)is a metabolic disease in which purine metabolic disorders lead to urate deposition in joint synovium and other tissues,causing inflammation of joints and local tissues,and even leading to joint deformity and injury,and often complicated with hyperlipidemia,fatty liver,hypertension,and kidney disease.In addition,if the complications of GA are not well controlled,it will accelerate the progression of GA,and even involve the urinary and cardiovascular systems.Western medicine treatment of GA complicated with hyperlipidemia(HLP)is mainly based on taking atorvastatin calcium and fenofibrate,but long-term use will cause liver function damage.Relatively speaking,traditional Chinese medicine can act on the disease through the effective components,multiple pathways and multiple targets,and has high safety and small adverse reactions.Based on this,this paper discusses the research progress of spleen-invigorating prescriptions in improving insulin resistance,regulating intestinal flora,anti-oxidative stress and reducing inflammatory factors by consulting relevant literature,and further clarifies the pathogenesis of GA complicated with HLP,so as to provide theoretical reference and scientific basis for the clinical application of traditional Chinese medicine in the prevention and treatment of GA complicated with HLP.关键词
痛风性关节炎/高脂血症/发病机制/从脾论治Key words
Gouty arthritis/Hyperlipidemia/Pathogenesis/Treatment from the spleen分类
临床医学引用本文复制引用
梁德风,江超宇,覃姻姻,徐家馨,庞学丰..痛风性关节炎并发高脂血症的发病机制及从脾论治的研究现状[J].医学信息,2024,37(14):188-192,5.
