跨越偏头痛急性与预防治疗的传统分界线OACSTPCD
Transcending the traditional dividing line between the acute and preventive treatment of migraine
偏头痛治疗分为急性和预防治疗,现有的偏头痛治疗指南通常将急性及预防治疗方案完全分开阐述,近年来部分研究发现二者联系密切.随着拮抗降钙素基因相关肽(CGRP)相关药物的问世,这类治疗方法可能超越了急性和预防性治疗药物之间的传统分界线,提供了一种全新的偏头痛治疗方法的可能性,即急性治疗可能有预防效益,预防治疗有急性的效果.同时,临床医生应该明确,急性和预防治疗并不是绝对独立的治疗模式,而是密切联系的治疗目标,最终目的都是为了更好地管理偏头痛.临床医生应根据患者自身情况制定个体化治疗方案,提高急性和预防治疗效果,减轻患者疾病负担.
The treatment of migraine is categorized into acute treatment and preventive treatment,and existing guidelines for the treatment of migraine usually describe the regimens for the two treatment methods separately,while some studies in recent years have found a close relationship between the two treatment methods.With the introduction of calcito-nin gene-related peptide-antagonizing drugs,such treatment methods may transcend the traditional dividing line between the acute and preventive treatment drugs,offering the possibility of an entirely new approach for the treatment of migraine,whereby acute treatment may have prophylactic benefits and prophylactic treatment may have the effect of acute treatment.At the same time,clinicians should understand that acute and preventive treatment methods are not absolutely indepen-dent treatment modes,and they are closely associated with each other,both with the ultimate goal of better migraine man-agement.Clinicians should develop individualized treatment regimens based on the specific condition of the patient,in or-der to improve the efficacy of acute and preventive treatment methods and reduce disease burden.
胥小诺;董亮;周冀英
重庆医科大学附属第一医院神经内科,重庆 400016
临床医学
偏头痛偏头痛急性治疗偏头痛预防治疗偏头痛慢性化
MigraineAcute treatment of migrainePreventive treatment of migraineMigraine chronicity
《中风与神经疾病杂志》 2024 (007)
582-585 / 4
国家重点研发计划"常见多发病防治研究"专项(2023YFC250703)
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