偏头痛发病机制及生物标志物研究进展OACSTPCD
Research advances in the pathogenesis and biomarkers of migraine
偏头痛是一种具有多种亚表型的异质性疾病,其诊断主要基于临床标准,缺乏特异性的生物标志物进行客观评估,影响了偏头痛的精确诊断、治疗选择以及预后评估.近年来偏头痛在遗传、生化、影像等方面研究取得重大进展,为临床诊断及治疗偏头痛提供了客观的检测指标.如能在临床工作中选择特异性、敏感性、易检测、可行性高的标志物将推动偏头痛早期诊断、精准化治疗的步伐.
Migraine is a heterogeneous disease with various subtypes,and the diagnosis of migraine mainly relies on clinical criteria.The lack of specific biomarkers for objective assessment impacts the precise diagnosis,treatment selec-tion,and prognostic assessment of migraine.In recent years,great progress has been made in migraine in terms of genet-ics,biochemistry,and imaging,which provides objective indicators for the clinical diagnosis and treatment of migraine.Identifying specific,sensitive,easily detectable,and highly feasible markers in clinical practice will accelerate the early di-agnosis and precise treatment of migraine.
毛西京;朱博驰;于挺敏
吉林大学第二医院,吉林 长春 130000
临床医学
偏头痛生物标志物神经元胶质细胞
MigraineBiomarkersNeuronsGlial cells
《中风与神经疾病杂志》 2024 (007)
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